Changing landscape of early phase clinical trials

Khanh Do; Chris H. Takimoto; Shivaani Kummar

doi:10.1016/B978-0-12-812512-0.00001-4

Changing landscape of early phase clinical trials

Khanh Do, Chris H. Takimoto, Shivaani Kummar

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

The field of oncology has evolved dramatically over the past 60 years. The growing complexity of clinical trials presents a number of logistical challenges, driving the escalating costs of drug development. As trial designs evolve to meet the pace of early drug development, financial considerations need to be taken into account in addition to safety and efficacy.

Original language	English (US)
Title of host publication	Novel Designs of Early Phase Trials for Cancer Therapeutics
Publisher	Elsevier
Pages	1-6
Number of pages	6
ISBN (Electronic)	9780128125120
ISBN (Print)	9780128125700
DOIs	https://doi.org/10.1016/B978-0-12-812512-0.00001-4
State	Published - Jan 1 2018
Externally published	Yes

Keywords

Drug approval
Molecular targeted agents
Precision medicine
Trial design

ASJC Scopus subject areas

General Medicine

Access to Document

10.1016/B978-0-12-812512-0.00001-4

Cite this

@inbook{c23a764ce7614a59a7b6de315621830f,

title = "Changing landscape of early phase clinical trials",

abstract = "The field of oncology has evolved dramatically over the past 60 years. The growing complexity of clinical trials presents a number of logistical challenges, driving the escalating costs of drug development. As trial designs evolve to meet the pace of early drug development, financial considerations need to be taken into account in addition to safety and efficacy.",

keywords = "Drug approval, Molecular targeted agents, Precision medicine, Trial design",

author = "Khanh Do and Takimoto, {Chris H.} and Shivaani Kummar",

year = "2018",

month = jan,

day = "1",

doi = "10.1016/B978-0-12-812512-0.00001-4",

language = "English (US)",

isbn = "9780128125700",

pages = "1--6",

booktitle = "Novel Designs of Early Phase Trials for Cancer Therapeutics",

publisher = "Elsevier",

}

TY - CHAP

T1 - Changing landscape of early phase clinical trials

AU - Do, Khanh

AU - Takimoto, Chris H.

AU - Kummar, Shivaani

PY - 2018/1/1

Y1 - 2018/1/1

N2 - The field of oncology has evolved dramatically over the past 60 years. The growing complexity of clinical trials presents a number of logistical challenges, driving the escalating costs of drug development. As trial designs evolve to meet the pace of early drug development, financial considerations need to be taken into account in addition to safety and efficacy.

AB - The field of oncology has evolved dramatically over the past 60 years. The growing complexity of clinical trials presents a number of logistical challenges, driving the escalating costs of drug development. As trial designs evolve to meet the pace of early drug development, financial considerations need to be taken into account in addition to safety and efficacy.

KW - Drug approval

KW - Molecular targeted agents

KW - Precision medicine

KW - Trial design

UR - http://www.scopus.com/inward/record.url?scp=85081361538&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85081361538&partnerID=8YFLogxK

U2 - 10.1016/B978-0-12-812512-0.00001-4

DO - 10.1016/B978-0-12-812512-0.00001-4

M3 - Chapter

AN - SCOPUS:85081361538

SN - 9780128125700

SP - 1

EP - 6

BT - Novel Designs of Early Phase Trials for Cancer Therapeutics

PB - Elsevier

ER -

Changing landscape of early phase clinical trials

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this