Abstract
The effects of photoreceptor cell degeneration on the expression of nine α-amino-3-hydroxy-5-methyl-isoxasole-4-propionate (AMPA)/kainate glutamate receptor subunit genes were investigated in the rd mouse retina by in situ hybridization. All known AMPA/kainate receptor subunits were found to be expressed in normal mouse retina. Following retinal degeneration, the expression of KA-1 was reduced, that of the GluR7 subunit was greatly increased, and that of the other seven subunits were not significantly affected.
Original language | English (US) |
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Pages (from-to) | 83-86 |
Number of pages | 4 |
Journal | Neuroscience Letters |
Volume | 183 |
Issue number | 1-2 |
DOIs | |
State | Published - Jan 2 1995 |
Keywords
- Glutamate receptor
- In situ hybridization
- Kainate
- Photoreceptor degeneration
- Retina
- rd mouse
- α-Andno-3-hydroxy-5-methyl-isoxasole-4-propionate
ASJC Scopus subject areas
- Neuroscience(all)