Abstract
The effects of photoreceptor cell degeneration on the expression of nine α-amino-3-hydroxy-5-methyl-isoxasole-4-propionate (AMPA)/kainate glutamate receptor subunit genes were investigated in the rd mouse retina by in situ hybridization. All known AMPA/kainate receptor subunits were found to be expressed in normal mouse retina. Following retinal degeneration, the expression of KA-1 was reduced, that of the GluR7 subunit was greatly increased, and that of the other seven subunits were not significantly affected.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 83-86 |
| Number of pages | 4 |
| Journal | Neuroscience Letters |
| Volume | 183 |
| Issue number | 1-2 |
| DOIs | |
| State | Published - Jan 2 1995 |
Keywords
- Glutamate receptor
- In situ hybridization
- Kainate
- Photoreceptor degeneration
- Retina
- rd mouse
- α-Andno-3-hydroxy-5-methyl-isoxasole-4-propionate
ASJC Scopus subject areas
- Neuroscience(all)
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Cite this
Duvoisin, R. M., Zhang, C., Hamassaki-Britto, D. E., & Britto, L. R. G. (1995). Changes in expression of glutamate receptor subunits following photoreceptor degeneration in the rd mouse retina. Neuroscience Letters, 183(1-2), 83-86. https://doi.org/10.1016/0304-3940(94)11120-8