ChIP-seq is a powerful method for obtaining genome-wide maps of protein-DNA interactions and epigeneticmodications. CHANCE (CHip-seq ANalytics and Condence Estimation) is a standalone package for ChIP-seqquality control and protocol optimization. Our user-friendly graphical software quickly estimates the strengthand quality of immunoprecipitations, identies biases, compares the user's data with ENCODE's large collectionof published datasets, performs multi-sample normalization, checks against qPCR-validated control regions, andproduces informative graphical reports. CHANCE is available at https://github.com/songlab/chance.
ASJC Scopus subject areas
- Ecology, Evolution, Behavior and Systematics
- Cell Biology
CHANCE : Comprehensive software for quality control andvalidation of ChIP-seq data. / Diaz, Aaron; Nellore, Abhinav; Song, Jun S.In: Genome Biology, 15.10.2012.
Research output: Contribution to journal › Article