CGHAnalyzer: A stand-alone software package for cancer genome analysis using array-based DNA copy number data

Adam A. Margolin, Joel Greshock, Tara L. Naylor, Yael Mosse, John M. Maris, Graham Bignell, Alexander I. Saeed, John Quackenbush, Barbara L. Weber

Research output: Contribution to journalArticle

25 Scopus citations

Abstract

Summary: This synopsis provides an overview of array-based comparative genomic hybridization data display, abstraction and analysis using CGHAnalyzer, a software suite, designed specifically for this purpose. CGHAnalyzer can be used to simultaneously load copy number data from multiple platforms, query and describe large, heterogeneous datasets and export results. Additionally, CGHAnalyzer employs a host of algorithms for microarray analysis that include hierarchical clustering and class differentiation.

Original languageEnglish (US)
Pages (from-to)3308-3311
Number of pages4
JournalBioinformatics
Volume21
Issue number15
DOIs
StatePublished - Aug 1 2005
Externally publishedYes

ASJC Scopus subject areas

  • Statistics and Probability
  • Biochemistry
  • Molecular Biology
  • Computer Science Applications
  • Computational Theory and Mathematics
  • Computational Mathematics

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    Margolin, A. A., Greshock, J., Naylor, T. L., Mosse, Y., Maris, J. M., Bignell, G., Saeed, A. I., Quackenbush, J., & Weber, B. L. (2005). CGHAnalyzer: A stand-alone software package for cancer genome analysis using array-based DNA copy number data. Bioinformatics, 21(15), 3308-3311. https://doi.org/10.1093/bioinformatics/bti500