CFTR: New Members Join the Fold

William Skach

Research output: Contribution to journalArticle

16 Scopus citations

Abstract

The folding, misfolding, and degradation of membrane proteins is controlled by multiple processes within the cell. In this issue of Cell, Wang et al. (2006) present an interactome for CFTR, the chloride channel that is misfolded and prematurely degraded in cystic fibrosis. Among the proteins interacting with CFTR is a new member of the Hsp90 chaperone system, Aha1, that plays a central role in CFTR folding.

Original languageEnglish (US)
Pages (from-to)673-675
Number of pages3
JournalCell
Volume127
Issue number4
DOIs
Publication statusPublished - Nov 17 2006

    Fingerprint

ASJC Scopus subject areas

  • Cell Biology
  • Molecular Biology

Cite this