Cerebral embolic protection during endovascular arch replacement

Christine R. Herman, Christian Rosu, Cherrie Abraham

Research output: Contribution to journalArticle

Abstract

Despite excellent results in high volume centers, open repair of aortic arch pathology is highly invasive, and can result in significant morbidity and mortality in high risk patients. Near-total and hybrid approaches to aortic arch disease states have emerged as an alternative for patients deemed moderate to high risk for conventional repair. Advantages of these approaches include avoidance of extracorporeal circulation and hypothermic circulatory arrest as well as avoidance of cross clamping, all of which are not well tolerated in high risk patients. Anatomically high-risk patients with anastomotic aneurysms from previous arch reconstruction may also benefit from these less invasive approaches. Medical devices designed specifically for the aortic arch are developing at a rapid pace and continue to evolve. Dedicated devices for zone 0-2 aortic arch repair are currently available under special access or being studied in clinical trials. Unfortunately, stroke continues to be the Achilles heel of endovascular approaches to the aortic arch, with cerebral embolism being the culprit in the majority of such cases. This perspective article describes the epidemiology, procedures, and mitigation strategies for current near-total and hybrid approaches to aortic arch pathology, and specifically addresses current means of embolic protection and future direction.

Original languageEnglish (US)
Pages (from-to)400-408
Number of pages9
JournalAnnals of Cardiothoracic Surgery
Volume7
Issue number3
DOIs
StatePublished - May 1 2018

Fingerprint

Thoracic Aorta
Pathology
Intracranial Embolism
Equipment and Supplies
Aortic Diseases
Extracorporeal Circulation
Constriction
Aneurysm
Epidemiology
Stroke
Clinical Trials
Morbidity
Mortality

Keywords

  • Arch
  • Embolism
  • Endovascular
  • Protection
  • Stroke

ASJC Scopus subject areas

  • Surgery
  • Cardiology and Cardiovascular Medicine

Cite this

Cerebral embolic protection during endovascular arch replacement. / Herman, Christine R.; Rosu, Christian; Abraham, Cherrie.

In: Annals of Cardiothoracic Surgery, Vol. 7, No. 3, 01.05.2018, p. 400-408.

Research output: Contribution to journalArticle

Herman, Christine R. ; Rosu, Christian ; Abraham, Cherrie. / Cerebral embolic protection during endovascular arch replacement. In: Annals of Cardiothoracic Surgery. 2018 ; Vol. 7, No. 3. pp. 400-408.
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