Central ventilatory dysfunction in myelodysplasia

an independent determinant of survival

R. M. Hays, R. A. Jordan, J. F. McLaughlin, Robert Nickel, L. D. Fisher

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

Central ventilatory dysfunction (CVD) is a significant complication of myelodysplasia with Arnold-Chiari type II defect. The records of 616 patients with myelodysplasia were reviewed and CVD was documented in 35 cases (5.7 per cent): it was the single most common cause of death in this population. There was no significant association between CVD and level of lesion, severity of hydrocephalus, hemorrhage or infection. The effects of CVD may be variable, with some patients having spontaneous remission and others having severe, often fatal, disruption of ventilation.

Original languageEnglish (US)
Pages (from-to)366-370
Number of pages5
JournalDevelopmental Medicine and Child Neurology
Volume31
Issue number3
StatePublished - 1989
Externally publishedYes

Fingerprint

Spontaneous Remission
Survival
Hydrocephalus
Ventilation
Cause of Death
Hemorrhage
Infection
Population

ASJC Scopus subject areas

  • Clinical Neurology
  • Pediatrics, Perinatology, and Child Health
  • Neuroscience(all)

Cite this

Hays, R. M., Jordan, R. A., McLaughlin, J. F., Nickel, R., & Fisher, L. D. (1989). Central ventilatory dysfunction in myelodysplasia: an independent determinant of survival. Developmental Medicine and Child Neurology, 31(3), 366-370.

Central ventilatory dysfunction in myelodysplasia : an independent determinant of survival. / Hays, R. M.; Jordan, R. A.; McLaughlin, J. F.; Nickel, Robert; Fisher, L. D.

In: Developmental Medicine and Child Neurology, Vol. 31, No. 3, 1989, p. 366-370.

Research output: Contribution to journalArticle

Hays, RM, Jordan, RA, McLaughlin, JF, Nickel, R & Fisher, LD 1989, 'Central ventilatory dysfunction in myelodysplasia: an independent determinant of survival', Developmental Medicine and Child Neurology, vol. 31, no. 3, pp. 366-370.
Hays, R. M. ; Jordan, R. A. ; McLaughlin, J. F. ; Nickel, Robert ; Fisher, L. D. / Central ventilatory dysfunction in myelodysplasia : an independent determinant of survival. In: Developmental Medicine and Child Neurology. 1989 ; Vol. 31, No. 3. pp. 366-370.
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