Cellular mechanisms of baroreceptor integration at the nucleus tractus solitarius

M. C. Andresen, M. W. Doyle, Y. H. Jin, T. W. Bailey

Research output: Contribution to journalArticle

39 Scopus citations

Abstract

The autonomic nervous system makes important contributions to the homeostatic regulation of the heart and blood vessels through arterial baroreflexes, and yet our understanding of the central nervous system mechanisms is limited. The sensory synapse of baroreceptors in the nucleus tractus solitarius (NTS) is unique because its participation is obligatory in the baroreflex. Here we describe experiments targeting this synapse to provide greater understanding of the cellular mechanisms at the earliest stages of the baroreflex. Our approach utilizes electrophysiology, pharmacology, and anatomical tracers to identify and evaluate key elements of the sensory information processing in NTS.

Original languageEnglish (US)
Pages (from-to)132-141
Number of pages10
JournalAnnals of the New York Academy of Sciences
Volume940
DOIs
StatePublished - 2001

Keywords

  • Baroreceptor
  • Baroreflex
  • Glutamate
  • Nucleus of the solitary tract
  • Synaptic processing
  • Visceral sensory

ASJC Scopus subject areas

  • Neuroscience(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • History and Philosophy of Science

Fingerprint Dive into the research topics of 'Cellular mechanisms of baroreceptor integration at the nucleus tractus solitarius'. Together they form a unique fingerprint.

  • Cite this