Cell surface receptor for ecotropic host-range mouse retroviruses

a cationic amino acid transporter.

M. P. Kavanaugh, H. Wang, C. A. Boyd, R. A. North, David Kabat

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

The cell surface receptor for ecotropic host-range murine leukemia viruses is a sodium-independent transporter for essential cationic acids. Our evidence strongly identifies this receptor as the transporter system y+, which was previously characterized by transport assays. Mutational analysis indicates that transporter activity is not necessary for viral reception. Infection of cells with ecotropic retroviruses causes only a partial down-modulation of receptor expression on cell surfaces.

Original languageEnglish (US)
Pages (from-to)485-494
Number of pages10
JournalArchives of virology. Supplementum
Volume9
StatePublished - 1994
Externally publishedYes

Fingerprint

Basic Amino Acid Transport Systems
Host Specificity
Cell Surface Receptors
Retroviridae
Amino Acid Transport System y+
Murine Leukemia Viruses
Sodium
Acids
Infection

ASJC Scopus subject areas

  • Immunology and Microbiology(all)

Cite this

Kavanaugh, M. P., Wang, H., Boyd, C. A., North, R. A., & Kabat, D. (1994). Cell surface receptor for ecotropic host-range mouse retroviruses: a cationic amino acid transporter. Archives of virology. Supplementum, 9, 485-494.

Cell surface receptor for ecotropic host-range mouse retroviruses : a cationic amino acid transporter. / Kavanaugh, M. P.; Wang, H.; Boyd, C. A.; North, R. A.; Kabat, David.

In: Archives of virology. Supplementum, Vol. 9, 1994, p. 485-494.

Research output: Contribution to journalArticle

Kavanaugh, M. P. ; Wang, H. ; Boyd, C. A. ; North, R. A. ; Kabat, David. / Cell surface receptor for ecotropic host-range mouse retroviruses : a cationic amino acid transporter. In: Archives of virology. Supplementum. 1994 ; Vol. 9. pp. 485-494.
@article{648cf4aa6f11491c9393b8e7e1237fcd,
title = "Cell surface receptor for ecotropic host-range mouse retroviruses: a cationic amino acid transporter.",
abstract = "The cell surface receptor for ecotropic host-range murine leukemia viruses is a sodium-independent transporter for essential cationic acids. Our evidence strongly identifies this receptor as the transporter system y+, which was previously characterized by transport assays. Mutational analysis indicates that transporter activity is not necessary for viral reception. Infection of cells with ecotropic retroviruses causes only a partial down-modulation of receptor expression on cell surfaces.",
author = "Kavanaugh, {M. P.} and H. Wang and Boyd, {C. A.} and North, {R. A.} and David Kabat",
year = "1994",
language = "English (US)",
volume = "9",
pages = "485--494",
journal = "Archives of Virology, Supplement",
issn = "0939-1983",
publisher = "Springer Verlag",

}

TY - JOUR

T1 - Cell surface receptor for ecotropic host-range mouse retroviruses

T2 - a cationic amino acid transporter.

AU - Kavanaugh, M. P.

AU - Wang, H.

AU - Boyd, C. A.

AU - North, R. A.

AU - Kabat, David

PY - 1994

Y1 - 1994

N2 - The cell surface receptor for ecotropic host-range murine leukemia viruses is a sodium-independent transporter for essential cationic acids. Our evidence strongly identifies this receptor as the transporter system y+, which was previously characterized by transport assays. Mutational analysis indicates that transporter activity is not necessary for viral reception. Infection of cells with ecotropic retroviruses causes only a partial down-modulation of receptor expression on cell surfaces.

AB - The cell surface receptor for ecotropic host-range murine leukemia viruses is a sodium-independent transporter for essential cationic acids. Our evidence strongly identifies this receptor as the transporter system y+, which was previously characterized by transport assays. Mutational analysis indicates that transporter activity is not necessary for viral reception. Infection of cells with ecotropic retroviruses causes only a partial down-modulation of receptor expression on cell surfaces.

UR - http://www.scopus.com/inward/record.url?scp=0028309203&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028309203&partnerID=8YFLogxK

M3 - Article

VL - 9

SP - 485

EP - 494

JO - Archives of Virology, Supplement

JF - Archives of Virology, Supplement

SN - 0939-1983

ER -