Signal transduction pathways are used to convey messages of ligands into changes of biological activity of target cells. This chapter briefly reviews selected aspects of signal transduction where evidence exists of potential relevance for neurotoxicity and developmental neurotoxicity of chemicals. A few examples of exogenous compounds (lead, polychlorinated biphenyls, ethanol) which are believed to exert neurotoxic effects by interacting with specific signal transduction pathways are discussed.
|Original language||English (US)|
|Title of host publication||Nervous System and Behavioral Toxicology|
|Number of pages||12|
|State||Published - Aug 12 2010|
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