Cell Signaling and Neurotoxicity

L. G. Costa, G. Giordano, Marina Guizzetti

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

Abstract

Signal transduction pathways are used to convey messages of ligands into changes of biological activity of target cells. This chapter briefly reviews selected aspects of signal transduction where evidence exists of potential relevance for neurotoxicity and developmental neurotoxicity of chemicals. A few examples of exogenous compounds (lead, polychlorinated biphenyls, ethanol) which are believed to exert neurotoxic effects by interacting with specific signal transduction pathways are discussed.

Original languageEnglish (US)
Title of host publicationNervous System and Behavioral Toxicology
PublisherElsevier Inc.
Pages89-100
Number of pages12
Volume13
ISBN (Print)9780080468686
DOIs
StatePublished - Aug 12 2010
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

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    Costa, L. G., Giordano, G., & Guizzetti, M. (2010). Cell Signaling and Neurotoxicity. In Nervous System and Behavioral Toxicology (Vol. 13, pp. 89-100). Elsevier Inc.. https://doi.org/10.1016/B978-0-08-046884-6.01307-5