Carfilzomib associated thrombotic microangiopathy initially treated with therapeutic plasma exchange

Matthew R. Sullivan; Alexey V. Danilov; Frederick Lansigan; Nancy M. Dunbar

doi:10.1002/jca.21371

Carfilzomib associated thrombotic microangiopathy initially treated with therapeutic plasma exchange

Matthew R. Sullivan, Alexey V. Danilov, Frederick Lansigan, Nancy M. Dunbar

Research output: Contribution to journal › Article › peer-review

30 Scopus citations

Abstract

Drug associated thrombotic microangiopathy (TMA) is a rare event causing thrombocytopenia, microangiopathic anemia, renal failure, and neurologic abnormalities. Here, we present a case of TMA that occurred during the first cycle of treatment with carfilzomib for relapsed multiple myeloma.

Original language	English (US)
Pages (from-to)	308-310
Number of pages	3
Journal	Journal of Clinical Apheresis
Volume	30
Issue number	5
DOIs	https://doi.org/10.1002/jca.21371
State	Published - Oct 2015
Externally published	Yes

Keywords

carfilzomib
multiple myeloma
plasma exchange
thrombotic microangiopathy

ASJC Scopus subject areas

Hematology

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10.1002/jca.21371

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title = "Carfilzomib associated thrombotic microangiopathy initially treated with therapeutic plasma exchange",

abstract = "Drug associated thrombotic microangiopathy (TMA) is a rare event causing thrombocytopenia, microangiopathic anemia, renal failure, and neurologic abnormalities. Here, we present a case of TMA that occurred during the first cycle of treatment with carfilzomib for relapsed multiple myeloma.",

keywords = "carfilzomib, multiple myeloma, plasma exchange, thrombotic microangiopathy",

author = "Sullivan, {Matthew R.} and Danilov, {Alexey V.} and Frederick Lansigan and Dunbar, {Nancy M.}",

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year = "2015",

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AU - Sullivan, Matthew R.

AU - Danilov, Alexey V.

AU - Lansigan, Frederick

AU - Dunbar, Nancy M.

PY - 2015/10

Y1 - 2015/10

N2 - Drug associated thrombotic microangiopathy (TMA) is a rare event causing thrombocytopenia, microangiopathic anemia, renal failure, and neurologic abnormalities. Here, we present a case of TMA that occurred during the first cycle of treatment with carfilzomib for relapsed multiple myeloma.

AB - Drug associated thrombotic microangiopathy (TMA) is a rare event causing thrombocytopenia, microangiopathic anemia, renal failure, and neurologic abnormalities. Here, we present a case of TMA that occurred during the first cycle of treatment with carfilzomib for relapsed multiple myeloma.

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KW - multiple myeloma

KW - plasma exchange

KW - thrombotic microangiopathy

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Carfilzomib associated thrombotic microangiopathy initially treated with therapeutic plasma exchange

Abstract

Keywords

ASJC Scopus subject areas

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