Cardiovascular effects and efficacy of a hemostatic agent in periradicular surgery

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

The purpose of this study was to evaluate the hemostatic efficacy and systemic cardiovascular effects of CollaCote™ collagen sponges saturated with 2.25% racemic epinephrine during endodontic surgery. A total of 48 patients participated in the study. Patients received CollaCote-saline or CollaCote-epinephrine placed in the bony crypt, after which hemostatic efficacy was evaluated. Blood pressure and pulse rate was recorded before and after administration of the local anesthetic, after the application of the test solutions, and before the patient's dismissal. Results showed no significant difference in blood pressure or pulse rate between the experimental and control groups. In the CollaCote-saline group, five of six cases failed to achieve hemorrhage control. In the CollaCote-epinephrine group, 1 of 42 cases had no hemorrhage control. Two patients had slight but apparent intermittent bleeding. Complete hemostasis was achieved in 39 of 42 cases. In conclusion, the results suggest that CollaCote collagen sponges saturated with 2.25% racemic epinephrine provide excellent hemostasis with no evident changes in blood pressure or pulse rate.

Original languageEnglish (US)
Pages (from-to)379-383
Number of pages5
JournalJournal of Endodontics
Volume30
Issue number6
StatePublished - Jun 2004

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Hemostatics
Racepinephrine
Heart Rate
Porifera
Hemorrhage
Blood Pressure
Hemostasis
Epinephrine
Collagen
Endodontics
Local Anesthetics
CollaCote
Control Groups

ASJC Scopus subject areas

  • Dentistry(all)

Cite this

Cardiovascular effects and efficacy of a hemostatic agent in periradicular surgery. / Vy, Christina Hong; Baumgartner, John (Craig); Marshall, J (Gordon).

In: Journal of Endodontics, Vol. 30, No. 6, 06.2004, p. 379-383.

Research output: Contribution to journalArticle

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