Cardiovascular disease and long-chain omega-3 fatty acids

William S. Harris, Yongsoon Park, William L. Isley

Research output: Contribution to journalReview articlepeer-review

66 Scopus citations


Purpose of review: Of all known dietary factors, long-chain omega-3 fatty acids may be the most protective against death from coronary heart disease. New evidence has confirmed and refined the cardioprotective role of these fatty acids. Recent findings: Omega-3 fatty acid supplementation reduces the risk of sudden cardiac death and death from any cause within 4 months in post-myocardial infarction patients. Evidence continues to accrue for benefits in the primary prevention of coronary heart disease and stroke, and an anti-arrhythmogenic mechanism is emerging as the most likely explanation. Summary: Current evidence suggests that individuals with coronary artery disease may reduce their risk of sudden cardiac death by increasing their intake of long-chain omega-3 fatty acids by approximately 1 g per day.

Original languageEnglish (US)
Pages (from-to)9-14
Number of pages6
JournalCurrent opinion in lipidology
Issue number1
StatePublished - Feb 1 2003


  • Fish oil
  • Lipoproteins
  • Statins
  • Sudden cardiac death
  • Triglycerides

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Molecular Biology
  • Genetics
  • Nutrition and Dietetics
  • Cardiology and Cardiovascular Medicine
  • Cell Biology


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