Carcinoma Erysipeloides From Metastatic Cutaneous Squamous Cell Carcinoma Initially Mistaken for Intralymphatic Histiocytosis

Michael S. Heath, Christa Slaught, Alex Ortega Loayza, Stephanie Mengden

Research output: Contribution to journalArticle

Abstract

Intralymphatic histiocytosis is a rare dermatologic disorder, commonly associated with inflammatory disorders and rarely malignancy. Carcinoma erysipeloides (CE) is a rare pseudoinflammatory cutaneous eruption that resembles soft -tissue infections as result of intralymphatic metastasis and subsequent lymphatic obstruction. Breast carcinoma represents most of the CE cases, but rarely other malignancies are involved. This report discusses a patient with a history of cutaneous squamous cell carcinoma (SCC) of the temple, who was initially diagnosed with intralymphatic histiocytosis located on his upper extremity, resistant to treatment. Further dermatologic and pathologic review later revealed metastatic SCC restricted to the dermal lymphatics, creating a CE reaction, initially obscured by intralymphatic histiocytes. This case highlights the difficulty in diagnosing metastatic carcinoma when the malignant cells are accompanied by a dense histiocytic infiltrate. The case demonstrates a rare presentation of CE due to metastatic cutaneous SCC and highlights the need for persistent investigation when confronted with nonconforming pathology.

Original languageEnglish (US)
Pages (from-to)522-525
Number of pages4
JournalThe American Journal of dermatopathology
Volume41
Issue number7
DOIs
StatePublished - Jul 1 2019

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Histiocytosis
Squamous Cell Carcinoma
Carcinoma
Skin
Lymphatic Metastasis
Soft Tissue Infections
Histiocytes
Upper Extremity
Neoplasms
Pathology
Breast Neoplasms

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Dermatology

Cite this

Carcinoma Erysipeloides From Metastatic Cutaneous Squamous Cell Carcinoma Initially Mistaken for Intralymphatic Histiocytosis. / Heath, Michael S.; Slaught, Christa; Ortega Loayza, Alex; Mengden, Stephanie.

In: The American Journal of dermatopathology, Vol. 41, No. 7, 01.07.2019, p. 522-525.

Research output: Contribution to journalArticle

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