Carboxylate as the protonation site in (peroxo)diiron(III) model complexes of soluble methane monooxygenase and related diiron proteins

Loi H. Do, Takahiro Hayashi, Pierre Moënne-Loccoz, Stephen J. Lippard

Research output: Contribution to journalArticlepeer-review

38 Scopus citations

Abstract

(Chemical Equation Presented) Addition of H+ to a synthetic (μ-1,2-peroxo)diiron(III) model complex results in protonation of a carboxylate rather than the peroxo ligand. This conclusion is based on spectroscopic evidence from UV-vis, 57Fe Mössbauer, resonance Raman, infrared, and 1H/19F NMR studies. These results suggest a similar role for protons in the dioxygen activation reactions in soluble methane monooxygenase and related carboxylate-bridged diiron enzymes.

Original languageEnglish (US)
Pages (from-to)1273-1275
Number of pages3
JournalJournal of the American Chemical Society
Volume132
Issue number4
DOIs
StatePublished - Feb 3 2010

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

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