Carboxyhemoglobinemia caused by inhalation of methylene chloride

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Spray-paint inhalation, once a common and inexpensive source of drug abuse, is now rare. Newer organic solvents, such as methylene chloride, were thought to decrease the toxicity of aerosol solvents, but they carry unique toxicities of their own. Methylene chloride toxicity is difficult to diagnose, as early symptoms are similar to those associated with many intoxicants; however, a rising carboxyhemoglobin level, despite removal of the patient from the source of exposure, is pathognomonic. In dealing with industrial exposures or organic aerosol abuse, a carboxyhemoglobin level should be part of the initial diagnostic workup, and treatment with oxygen is mandatory until toxicity resolves.

Original languageEnglish (US)
Pages (from-to)48-51
Number of pages4
JournalAmerican Journal of Emergency Medicine
Volume4
Issue number1
DOIs
StatePublished - 1986
Externally publishedYes

Fingerprint

Carboxyhemoglobin
Methylene Chloride
Aerosols
Inhalation
Paint
Substance-Related Disorders
Oxygen
Therapeutics

Keywords

  • Carbon monoxide
  • carboxyhemoglobinemia
  • methylene chloride
  • paint inhalation

ASJC Scopus subject areas

  • Emergency Medicine

Cite this

Carboxyhemoglobinemia caused by inhalation of methylene chloride. / Horowitz, B (Zane).

In: American Journal of Emergency Medicine, Vol. 4, No. 1, 1986, p. 48-51.

Research output: Contribution to journalArticle

@article{7cae59a0eb644c61bf3b7d86612ea804,
title = "Carboxyhemoglobinemia caused by inhalation of methylene chloride",
abstract = "Spray-paint inhalation, once a common and inexpensive source of drug abuse, is now rare. Newer organic solvents, such as methylene chloride, were thought to decrease the toxicity of aerosol solvents, but they carry unique toxicities of their own. Methylene chloride toxicity is difficult to diagnose, as early symptoms are similar to those associated with many intoxicants; however, a rising carboxyhemoglobin level, despite removal of the patient from the source of exposure, is pathognomonic. In dealing with industrial exposures or organic aerosol abuse, a carboxyhemoglobin level should be part of the initial diagnostic workup, and treatment with oxygen is mandatory until toxicity resolves.",
keywords = "Carbon monoxide, carboxyhemoglobinemia, methylene chloride, paint inhalation",
author = "Horowitz, {B (Zane)}",
year = "1986",
doi = "10.1016/0735-6757(86)90251-2",
language = "English (US)",
volume = "4",
pages = "48--51",
journal = "American Journal of Emergency Medicine",
issn = "0735-6757",
publisher = "W.B. Saunders Ltd",
number = "1",

}

TY - JOUR

T1 - Carboxyhemoglobinemia caused by inhalation of methylene chloride

AU - Horowitz, B (Zane)

PY - 1986

Y1 - 1986

N2 - Spray-paint inhalation, once a common and inexpensive source of drug abuse, is now rare. Newer organic solvents, such as methylene chloride, were thought to decrease the toxicity of aerosol solvents, but they carry unique toxicities of their own. Methylene chloride toxicity is difficult to diagnose, as early symptoms are similar to those associated with many intoxicants; however, a rising carboxyhemoglobin level, despite removal of the patient from the source of exposure, is pathognomonic. In dealing with industrial exposures or organic aerosol abuse, a carboxyhemoglobin level should be part of the initial diagnostic workup, and treatment with oxygen is mandatory until toxicity resolves.

AB - Spray-paint inhalation, once a common and inexpensive source of drug abuse, is now rare. Newer organic solvents, such as methylene chloride, were thought to decrease the toxicity of aerosol solvents, but they carry unique toxicities of their own. Methylene chloride toxicity is difficult to diagnose, as early symptoms are similar to those associated with many intoxicants; however, a rising carboxyhemoglobin level, despite removal of the patient from the source of exposure, is pathognomonic. In dealing with industrial exposures or organic aerosol abuse, a carboxyhemoglobin level should be part of the initial diagnostic workup, and treatment with oxygen is mandatory until toxicity resolves.

KW - Carbon monoxide

KW - carboxyhemoglobinemia

KW - methylene chloride

KW - paint inhalation

UR - http://www.scopus.com/inward/record.url?scp=0022653803&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0022653803&partnerID=8YFLogxK

U2 - 10.1016/0735-6757(86)90251-2

DO - 10.1016/0735-6757(86)90251-2

M3 - Article

VL - 4

SP - 48

EP - 51

JO - American Journal of Emergency Medicine

JF - American Journal of Emergency Medicine

SN - 0735-6757

IS - 1

ER -