Cancer of the minor salivary glands of the larynx

James Cohen, Oscar M. Guillamondegui, John G. Batsakis, Jesus E. Medina

Research output: Contribution to journalArticle

32 Scopus citations

Abstract

Minor salivary gland carcinomas of the larynx are rare and few large series have been reported from a single institution. Eighteen patients were treated for this disease at M.D. Anderson Hospital between 1944 and 1982. Of these, 8 patients had adenoid cystic carcinoma and 10 had poorly differentiated adenocarcinoma. Characteristically these tumors presented as predominantly submucosal masses in the supraglottic or subglottic regions. Surgery was the primary treatment modality used in most cases. The average 2 and 5 year survival rates for patients with this disease were 70.6 percent and 42.8 percent, respectively. Although the 5 year survival rates were comparable between the adenocarcinoma and cystic carcinoma groups, adenocarcinoma was a more rapidly lethal disease than adenoid cystic carcinoma. Salvage after recurrence was seldom possible, although local and regional control could usually be achieved. Distant metastases remain the principal cause of treatment failure.

Original languageEnglish (US)
Pages (from-to)513-518
Number of pages6
JournalThe American Journal of Surgery
Volume150
Issue number4
DOIs
StatePublished - Oct 1985

ASJC Scopus subject areas

  • Surgery

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