Cancer-Attributable Costs of Diagnosis and Care for Persons with Screen-Detected Versus Symptom-Detected Colorectal Cancer

Scott D. Ramsey, Margaret T. Mandelson, Kristin Berry, Ruth Etzioni, Robert Harrison

Research output: Contribution to journalArticlepeer-review

38 Scopus citations


Background & Aims: Colorectal cancer screening is effective and cost-effective, but little data from health plan settings are available inform decision-makers regarding direct economic implications of colorectal cancer screening programs. The purpose of this study was to compare the prediagnosis evaluation and first-year treatment costs of persons diagnosed with colorectal cancer, stratified by whether the cancer was detected by screening using fecal occult blood testing or evaluation of symptoms. Methods: This retrospective study analyzed persons diagnosed with colorectal cancer from 1993 to 1999 in Group Health Cooperative, a large health maintenance organization in Washington state. Total health care costs during 3 months before and 12 months following diagnosis were compared for screen-detected versus symptom-detected individuals. Results: During this time, 206 cancers were detected by screening and 717 by symptoms. In the 3 months before diagnosis, total costs were $7346 for persons with screen-detected versus $10,042 for those with symptom-detected cancer (P < 0.01). Stratified by stage, diagnosis costs were significantly lower for persons with stage B cancer ($7282 vs. $11,682; P < 0.01) and nonsignificantly lower for other stages. A total of 53% of screen-detected cases were Dukes' stage A or in situ at diagnosis versus 30% of symptom-detected cases (P < 0.01). Overall costs were lower for the screen-detected group in the 12 months following diagnosis ($22,369 vs. $29,471; P < 0.01). Conclusions: Colorectal cancer screening can substantially reduce prediagnosis evaluation costs. These savings are of interest to health plans and should be factored into cost-effectiveness evaluations of screening programs.

Original languageEnglish (US)
Pages (from-to)1645-1650
Number of pages6
Issue number6
StatePublished - Dec 2003
Externally publishedYes

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology


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