TY - JOUR
T1 - Can a Minimal Clinically Important Difference Be Achieved in Elderly Patients with Adult Spinal Deformity Who Undergo Minimally Invasive Spinal Surgery?
AU - International Spine Study Group
AU - Park, Paul
AU - Okonkwo, David O.
AU - Nguyen, Stacie
AU - Mundis, Gregory M.
AU - Than, Khoi D.
AU - Deviren, Vedat
AU - La Marca, Frank
AU - Fu, Kai Ming
AU - Wang, Michael Y.
AU - Uribe, Juan S.
AU - Anand, Neel
AU - Fessler, Richard
AU - Nunley, Pierce D.
AU - Chou, Dean
AU - Kanter, Adam S.
AU - Shaffrey, Christopher I.
AU - Akbarnia, Behrooz A.
AU - Passias, Peter G.
AU - Eastlack, Robert K.
AU - Mummaneni, Praveen V.
N1 - Funding Information:
The authors report the following: N.A.: consultant for Medtronic, Globus Medical, and Baxano Surgical; direct stock ownership in Globus Medical and Medtronic; receiving royalties from Medtronic, Globus Medical, NuVasive, and Baxano Surgical. V.D.: consultant for NuVasive, Guidepoint, and Stryker’ A.S.K.: consultant for NuVasive; receiving royalties from Lanx. F.L.M.: consultant for Globus Medical and Biomet; patent holder with Globus Medical; receiving nonstudy-related clinical/research support from Globus Medical. P.V.M.: direct stock ownership in Spinicity; receiving royalties from DePuy Spine, Quality Medical Publisher, and Thieme Publishers; received honoraria from Globus Medical. G.M.M.: consultant for and receiving royalties from NuVasive and K2M. D.O.O.: receiving royalties from Lanx. P.P.: consultant for Medtronic, Globus Medical, and Biomet; receiving royalties from Globus Medical; receiving nonstudy-related clinical/research support from Orthofix, Blue Care Blue Cross Foundation. C.I.S.: consultant for Biomet, Globus Medical, Medtronic, NuVasive, and Stryker; patent holder with Biomet and Medtronic; receiving royalties from Biomet and Medtronic. J.S.U.: consultant for NuVasive. M.Y.W.: consultant for Aesculap Spine and DePuy Spine; patent holder with DePuy Spine.
Funding Information:
Conflict of interest statement: The authors report the following: N.A.: consultant for Medtronic, Globus Medical, and Baxano Surgical; direct stock ownership in Globus Medical and Medtronic; receiving royalties from Medtronic, Globus Medical, NuVasive, and Baxano Surgical. V.D.: consultant for NuVasive, Guidepoint, and Stryker’ A.S.K.: consultant for NuVasive; receiving royalties from Lanx. F.L.M.: consultant for Globus Medical and Biomet; patent holder with Globus Medical; receiving nonstudy-related clinical/research support from Globus Medical. P.V.M.: direct stock ownership in Spinicity; receiving royalties from DePuy Spine, Quality Medical Publisher, and Thieme Publishers; received honoraria from Globus Medical. G.M.M.: consultant for and receiving royalties from NuVasive and K2M. D.O.O.: receiving royalties from Lanx. P.P.: consultant for Medtronic, Globus Medical, and Biomet; receiving royalties from Globus Medical; receiving nonstudy-related clinical/research support from Orthofix, Blue Care Blue Cross Foundation. C.I.S.: consultant for Biomet, Globus Medical, Medtronic, NuVasive, and Stryker; patent holder with Biomet and Medtronic; receiving royalties from Biomet and Medtronic. J.S.U.: consultant for NuVasive. M.Y.W.: consultant for Aesculap Spine and DePuy Spine; patent holder with DePuy Spine.
Publisher Copyright:
© 2016 Elsevier Inc. All rights reserved.
PY - 2016/2
Y1 - 2016/2
N2 - Background Older age has been considered a relative contraindication to complex spinal procedures. Minimally invasive surgery (MIS) techniques to treat patients with adult spinal deformity (ASD) have emerged with the potential benefit of decreased approach-related morbidity. Objective To determine whether a minimal clinically important difference (MCID) could be achieved in patients ages ≥65 years with ASD who underwent MIS. Methods Multicenter database of patients who underwent MIS for ASD was queried. Outcome metrics assessed were Oswestry Disability Index (ODI) and visual analog scale (VAS) scores for back and leg pain. On the basis of published reports, MCID was defined as a positive change of 12.8 ODI, 1.2 VAS back pain, and 1.6 VAS leg pain. Results Forty-two patients were identified. Mean age was 70.3 years; 31 (73.8%) were women. Preoperatively, mean coronal curve, pelvic tilt, pelvic incidence to lumbar lordosis mismatch, and sagittal vertical axis were 35°, 24.6°, 14.2°, and 4.7 cm, respectively. Postoperatively, mean coronal curve, pelvic tilt, pelvic incidence to lumbar lordosis, and sagittal vertical axis were 18°, 25.4°, 11.9°, and 4.9 cm, respectively. A mean of 5.0 levels was treated posteriorly, and a mean of 4.0 interbody fusions was performed. Mean ODI improved from 47.1 to 25.1. Mean VAS back and leg pain scores improved from 6.8 and 5.9 to 2.7 and 2.7, respectively. Mean follow-up was 32.1 months. For ODI, 64.3% of patients achieved MCID. For VAS back and leg pain, 82.9% and 72.2%, respectively, reached MCID. Conclusions MCID represents the threshold at which patients feel a meaningful clinical improvement has occurred. Our study results suggest that the majority of elderly patients with modest ASD can achieve MCID with MIS.
AB - Background Older age has been considered a relative contraindication to complex spinal procedures. Minimally invasive surgery (MIS) techniques to treat patients with adult spinal deformity (ASD) have emerged with the potential benefit of decreased approach-related morbidity. Objective To determine whether a minimal clinically important difference (MCID) could be achieved in patients ages ≥65 years with ASD who underwent MIS. Methods Multicenter database of patients who underwent MIS for ASD was queried. Outcome metrics assessed were Oswestry Disability Index (ODI) and visual analog scale (VAS) scores for back and leg pain. On the basis of published reports, MCID was defined as a positive change of 12.8 ODI, 1.2 VAS back pain, and 1.6 VAS leg pain. Results Forty-two patients were identified. Mean age was 70.3 years; 31 (73.8%) were women. Preoperatively, mean coronal curve, pelvic tilt, pelvic incidence to lumbar lordosis mismatch, and sagittal vertical axis were 35°, 24.6°, 14.2°, and 4.7 cm, respectively. Postoperatively, mean coronal curve, pelvic tilt, pelvic incidence to lumbar lordosis, and sagittal vertical axis were 18°, 25.4°, 11.9°, and 4.9 cm, respectively. A mean of 5.0 levels was treated posteriorly, and a mean of 4.0 interbody fusions was performed. Mean ODI improved from 47.1 to 25.1. Mean VAS back and leg pain scores improved from 6.8 and 5.9 to 2.7 and 2.7, respectively. Mean follow-up was 32.1 months. For ODI, 64.3% of patients achieved MCID. For VAS back and leg pain, 82.9% and 72.2%, respectively, reached MCID. Conclusions MCID represents the threshold at which patients feel a meaningful clinical improvement has occurred. Our study results suggest that the majority of elderly patients with modest ASD can achieve MCID with MIS.
KW - Adult spinal deformity
KW - Elderly
KW - Minimally invasive surgery
KW - Spine
UR - http://www.scopus.com/inward/record.url?scp=84959346726&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84959346726&partnerID=8YFLogxK
U2 - 10.1016/j.wneu.2015.09.072
DO - 10.1016/j.wneu.2015.09.072
M3 - Article
C2 - 26431736
AN - SCOPUS:84959346726
VL - 86
SP - 168
EP - 172
JO - World Neurosurgery
JF - World Neurosurgery
SN - 1878-8750
ER -