Caged lipids for subcellular manipulation

Scotland Farley, Aurélien Laguerre, Carsten Schultz

Research output: Contribution to journalReview articlepeer-review

7 Scopus citations

Abstract

We present recently developed strategies to manipulate lipid levels in live cells by light. We focus on photoremovable protecting groups that lead to subcellular restricted localization and activation and discuss alternative techniques. We emphasize the development of organelle targeting of caged lipids and discuss recent advances in chromatic orthogonality of caging groups for future applications.

Original languageEnglish (US)
Pages (from-to)42-48
Number of pages7
JournalCurrent Opinion in Chemical Biology
Volume65
DOIs
StatePublished - Dec 2021
Externally publishedYes

Keywords

  • Fluorescence
  • Lipid transport
  • Photoactivation
  • Signaling

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry

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