C-reactive protein levels in patients with aggressive periodontitis

Trang N. Salzberg, Benjamin T. Overstreet, Jeffrey D. Rogers, Joseph Califano, Al M. Best, Harvey A. Schenkein

Research output: Contribution to journalArticle

74 Citations (Scopus)

Abstract

Background: Sera from patients with periodontal infections contain elevated levels of C-reactive protein (CRP) compared to periodontally healthy individuals. Most studies to date have included patients with chronic periodontitis, and few investigators have studied CRP levels in subjects with aggressive periodontitis (AgP). The purpose of this study was to determine the relative levels of serum CRP in AgP patients and periodontally healthy subjects and to examine patients' characteristics that might account for intergroup differences. Methods: Serum samples were collected from 93 patients with generalized AgP (GAgP), from 97 patients with localized AgP (LAgP), and from 91 healthy controls (non-periodontitis [NP]). Periodontal examination consisted of plaque index, gingival index, probing depth, bleeding index, and attachment loss measurements. Current smoking was assessed by determination of serum cotinine levels by enzyme-linked immunosorbent assay (ELISA), and serum CRP levels were determined using a high-sensitivity ELISA assay. Results: The three groups were significantly different from one another (P

Original languageEnglish (US)
Pages (from-to)933-939
Number of pages7
JournalJournal of Periodontology
Volume77
Issue number6
DOIs
StatePublished - Jun 2006
Externally publishedYes

Fingerprint

Aggressive Periodontitis
C-Reactive Protein
Blood Proteins
Serum
Enzyme-Linked Immunosorbent Assay
Periodontal Index
Cotinine
Chronic Periodontitis
Healthy Volunteers
Smoking
Research Personnel
Hemorrhage
Infection

Keywords

  • Aggressive periodontitis
  • C-reactive protein
  • Periodontal attachment loss

ASJC Scopus subject areas

  • Dentistry(all)

Cite this

Salzberg, T. N., Overstreet, B. T., Rogers, J. D., Califano, J., Best, A. M., & Schenkein, H. A. (2006). C-reactive protein levels in patients with aggressive periodontitis. Journal of Periodontology, 77(6), 933-939. https://doi.org/10.1902/jop.2006.050165

C-reactive protein levels in patients with aggressive periodontitis. / Salzberg, Trang N.; Overstreet, Benjamin T.; Rogers, Jeffrey D.; Califano, Joseph; Best, Al M.; Schenkein, Harvey A.

In: Journal of Periodontology, Vol. 77, No. 6, 06.2006, p. 933-939.

Research output: Contribution to journalArticle

Salzberg, TN, Overstreet, BT, Rogers, JD, Califano, J, Best, AM & Schenkein, HA 2006, 'C-reactive protein levels in patients with aggressive periodontitis', Journal of Periodontology, vol. 77, no. 6, pp. 933-939. https://doi.org/10.1902/jop.2006.050165
Salzberg, Trang N. ; Overstreet, Benjamin T. ; Rogers, Jeffrey D. ; Califano, Joseph ; Best, Al M. ; Schenkein, Harvey A. / C-reactive protein levels in patients with aggressive periodontitis. In: Journal of Periodontology. 2006 ; Vol. 77, No. 6. pp. 933-939.
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