Burden of spinal cord injury-related neuropathic pain in the United States: Retrospective chart review and cross-sectional survey

R. Mann, C. Schaefer, A. Sadosky, F. Bergstrom, R. Baik, B. Parsons, S. Nalamachu, B. R. Stacey, M. Tuchman, A. Anschel, E. C. Nieshoff

Research output: Contribution to journalArticle

53 Citations (Scopus)

Abstract

Study design:Cross-sectional, observational study.Objectives:Characterize demographic and clinical characteristics, health status, pain, function, productivity and economic burden in spinal cord injury-related neuropathic pain (SCI-NeP) subjects, by pain severity.Setting:United States.Methods:One hundred and three subjects diagnosed with SCI-NeP recruited during routine primary care or specialty physician office visits completed a questionnaire to assess patient-reported outcomes. Physicians completed a case report form on inclusion/exclusion criteria, subject clinical characteristics and health-care resource use (HRU) based on 6-month retrospective chart review.Results:Subjects' mean age was 48.7, 69.9% were male and 48.5% were unable to walk. The most frequently reported comorbidities were sleep disturbance/insomnia (28.2%), depressive symptoms (25.2%) and anxiety (23.3%). Subjects' mean pain severity score was 5.3 (0-10 scale), and 77.7% reported moderate or severe pain. On a 0-10 scale, subjects' reported moderate pain interference with function: mean 5.4. Subjects' health status, as measured by the EuroQol 5-dimensions health-state utility, was 0.49 (-0.11 to 1.00 scale). Pain interference with function and health status were significantly worse among subjects with more severe pain (P

Original languageEnglish (US)
Pages (from-to)564-570
Number of pages7
JournalSpinal Cord
Volume51
Issue number7
DOIs
StatePublished - Jul 2013

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Neuralgia
Spinal Cord Injuries
Cross-Sectional Studies
Pain
Health Status
Office Visits
Physicians' Offices
Health Resources
Sleep Initiation and Maintenance Disorders
Observational Studies
Comorbidity
Primary Health Care
Sleep
Anxiety
Economics
Demography
Depression
Delivery of Health Care
Physicians
Health

Keywords

  • burden of illness
  • costs
  • health-care resource use
  • productivity
  • quality-of-life
  • spinal cord injury-related neuropathic pain

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

Cite this

Mann, R., Schaefer, C., Sadosky, A., Bergstrom, F., Baik, R., Parsons, B., ... Nieshoff, E. C. (2013). Burden of spinal cord injury-related neuropathic pain in the United States: Retrospective chart review and cross-sectional survey. Spinal Cord, 51(7), 564-570. https://doi.org/10.1038/sc.2013.34

Burden of spinal cord injury-related neuropathic pain in the United States : Retrospective chart review and cross-sectional survey. / Mann, R.; Schaefer, C.; Sadosky, A.; Bergstrom, F.; Baik, R.; Parsons, B.; Nalamachu, S.; Stacey, B. R.; Tuchman, M.; Anschel, A.; Nieshoff, E. C.

In: Spinal Cord, Vol. 51, No. 7, 07.2013, p. 564-570.

Research output: Contribution to journalArticle

Mann, R, Schaefer, C, Sadosky, A, Bergstrom, F, Baik, R, Parsons, B, Nalamachu, S, Stacey, BR, Tuchman, M, Anschel, A & Nieshoff, EC 2013, 'Burden of spinal cord injury-related neuropathic pain in the United States: Retrospective chart review and cross-sectional survey', Spinal Cord, vol. 51, no. 7, pp. 564-570. https://doi.org/10.1038/sc.2013.34
Mann, R. ; Schaefer, C. ; Sadosky, A. ; Bergstrom, F. ; Baik, R. ; Parsons, B. ; Nalamachu, S. ; Stacey, B. R. ; Tuchman, M. ; Anschel, A. ; Nieshoff, E. C. / Burden of spinal cord injury-related neuropathic pain in the United States : Retrospective chart review and cross-sectional survey. In: Spinal Cord. 2013 ; Vol. 51, No. 7. pp. 564-570.
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