Buerger's disease

Phong T. Dargon, Gregory J. Landry

    Research output: Contribution to journalArticlepeer-review

    48 Scopus citations


    Buerger's disease (thromboangiitis obliterans) is a nonatherosclerotic segmental inflammatory disease of small- and medium-sized arteries of the distal extremities of predominantly young male tobacco users. Early symptoms may include episodic pain and coldness in fingers, and late findings may present as intermittent claudication, skin ulcers, or gangrene requiring eventual amputation. Tobacco cessation is the cornerstone of treatment. Other modalities of reducing pain or avoiding amputation have not been as successful. This review summarizes in tabular form the types of treatment that have been used, including therapeutic angiogenesis.

    Original languageEnglish (US)
    Pages (from-to)871-880
    Number of pages10
    JournalAnnals of Vascular Surgery
    Issue number6
    StatePublished - Aug 2012

    ASJC Scopus subject areas

    • Surgery
    • Cardiology and Cardiovascular Medicine


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