Bronchioloalveolar Carcinoma

Clinical, Histopathologic, and Radiologic Findings

Kyung Soo Lee, Yookyung Kim, Jungho Han, Eun Joo Ko, Choong Ki Park, Steven Primack

Research output: Contribution to journalArticle

117 Citations (Scopus)

Abstract

Bronchioloalveolar carcinoma is characterized pathologically by a pulmonary neoplasm showing lepidic growth. More than half of all patients with bronchioloalveolar carcinoma are asymptomatic. The most frequent symptoms and signs are cough, sputum, shortness of breath, weight loss, hemoptysis, and fever. Bronchorrhea is unusual and a late manifestation. Nonmucinous bronchioloalveolar carcinoma tends to be more localized and has a lower frequency of bronchogenic spread than mucinous bronchioloalveolar carcinoma. Bronchioloalveolar carcinoma appears radiographically as a single nodule, segmental or lobar consolidation, or diffuse nodules. At computed tomography (CT), the single nodular form appears as a peripheral nodule or localized ground-glass attenuation with or without consolidation, frequently associated with bubblelike areas of low attenuation and open bronchus signs. The lobar consolidative form may demonstrate the CT angiogram and open bronchus signs. The diffuse nodular form appears as multiple nodules or areas of ground-glass attenuation or consolidation. The single nodular form has a better prognosis than the others but may show false-negative results for malignancy at 2-(fluorine-18) fluoro-2-deoxy-D-glucose positron emission tomography.

Original languageEnglish (US)
Pages (from-to)1345-1357
Number of pages13
JournalRadiographics
Volume17
Issue number6
StatePublished - Nov 1997

Fingerprint

Bronchiolo-Alveolar Adenocarcinoma
Bronchi
Glass
Tomography
Mucinous Adenocarcinoma
Hemoptysis
Fluorine
Deoxyglucose
Sputum
Cough
Positron-Emission Tomography
Dyspnea
Signs and Symptoms
Weight Loss
Lung Neoplasms
Angiography
Fever
Growth
Neoplasms

Keywords

  • Lung neoplasms, CT, 60.1211
  • Lung neoplasms, diagnosis, 60.3216
  • Lung neoplasms, staging, 60.3216

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Lee, K. S., Kim, Y., Han, J., Ko, E. J., Park, C. K., & Primack, S. (1997). Bronchioloalveolar Carcinoma: Clinical, Histopathologic, and Radiologic Findings. Radiographics, 17(6), 1345-1357.

Bronchioloalveolar Carcinoma : Clinical, Histopathologic, and Radiologic Findings. / Lee, Kyung Soo; Kim, Yookyung; Han, Jungho; Ko, Eun Joo; Park, Choong Ki; Primack, Steven.

In: Radiographics, Vol. 17, No. 6, 11.1997, p. 1345-1357.

Research output: Contribution to journalArticle

Lee, KS, Kim, Y, Han, J, Ko, EJ, Park, CK & Primack, S 1997, 'Bronchioloalveolar Carcinoma: Clinical, Histopathologic, and Radiologic Findings', Radiographics, vol. 17, no. 6, pp. 1345-1357.
Lee, Kyung Soo ; Kim, Yookyung ; Han, Jungho ; Ko, Eun Joo ; Park, Choong Ki ; Primack, Steven. / Bronchioloalveolar Carcinoma : Clinical, Histopathologic, and Radiologic Findings. In: Radiographics. 1997 ; Vol. 17, No. 6. pp. 1345-1357.
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