Bringing research to the bedside: The role of induced hypothermia in cardiac arrest

Lisa Cushman, Mary Lou Warren, Sarah Livesay

Research output: Contribution to journalReview articlepeer-review

11 Scopus citations


Despite progress in resuscitative practices, there has been little improvement in mortality and neurologic morbidity outcomes after cardiac arrest. Updated resuscitative guidelines were published in 2005, and included changes in resuscitation measures and recommendations in postresuscitation interventions including induced hypothermia. Treatment with induced hypothermia after cardiac arrest for up to 24 hours has been shown to significantly improve the neurologic outcomes and mortality in patients with primary cardiac arrest who remain comatose after return of spontaneous circulation. St. Luke's Episcopal Hospital, a private, not-for-profit teaching hospital licensed for 949 beds located at the Texas Medical Center in Houston, Tex, has incorporated this research into practice. A multidisciplinary team led by a neurointensivist was formed to develop and implement a protocol to support induced hypothermia after cardiac arrest. Twenty-five patients have received induced hypothermia with a 74% survival rate. Of those who survived, 47% went home for a regular discharge, 29% transferred to acute rehabilitation, and 23% transferred to a long-term care facility.

Original languageEnglish (US)
Pages (from-to)143-153
Number of pages11
JournalCritical Care Nursing Quarterly
Issue number2
StatePublished - Apr 2007
Externally publishedYes


  • Cardiac arrest
  • Implementation
  • Induced hypothermia
  • Protocol
  • Research

ASJC Scopus subject areas

  • Critical Care


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