Bringing Order to the Glutamate Chaos in Schizophrenia

Research output: Contribution to journalReview article

332 Scopus citations

Abstract

Recent genetic linkage studies complement the existing evidence that implicates abnormalities in NMDA receptor-mediated neurotransmission in the pathophysiology of schizophrenia. At the same time, advances in our understanding of the complex mechanisms that modulate the function of NMDA receptors suggest several novel sites for pharmacological manipulation of these receptors. This presents exciting opportunities for rational rather than serendipitous discovery of therapeutics for schizophrenia.

Original languageEnglish (US)
Pages (from-to)881-884
Number of pages4
JournalNeuron
Volume40
Issue number5
DOIs
StatePublished - Dec 4 2003

ASJC Scopus subject areas

  • Neuroscience(all)

Fingerprint Dive into the research topics of 'Bringing Order to the Glutamate Chaos in Schizophrenia'. Together they form a unique fingerprint.

  • Cite this