Brain-computer interface-based control of closed-loop brain stimulation: attitudes and ethical considerations

Eran Klein, Sara Goering, Josh Gagne, Conor V. Shea, Rachel Franklin, Samuel Zorowitz, Darin D. Dougherty, Alik S. Widge

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Patients who have undergone deep brain stimulation (DBS) for emerging indications have unique perspectives on ethical challenges that may shape trial design and identify key design features for BCI-driven DBS systems. DBS research in cognitive and emotional disorders has generated significant ethical interest. Much of this work has focused on developing ethical guidelines and recommendations for open-loop DBS systems. While early trials of open-loop DBS for depression gave disappointing results, research is moving toward clinical trials with closed-loop or patient-controllable DBS systems that may modulate aspects of personality and emotion. Though user-centered design is an increasingly important principle in neurotechnology, the perspectives of implanted individuals on ethical issues raised by DBS are poorly understood. We solicited those perspectives through a focus group and set of qualitative interviews of participants in trials of DBS for depression and obsessive-compulsive disorder. We identified four major themes: control over device function, authentic self, relationship effects, and meaningful consent. Each has implications for the design of closed-loop systems for non-motor disorders.

Original languageEnglish (US)
Pages (from-to)140-148
Number of pages9
JournalBrain-Computer Interfaces
Volume3
Issue number3
DOIs
StatePublished - Jul 2 2016

Fingerprint

Brain-Computer Interfaces
Brain computer interface
Deep Brain Stimulation
Brain
Depression
Obsessive-Compulsive Disorder
Focus Groups
Research
Closed loop systems
Ethics
Personality
Emotions
Clinical Trials
Guidelines
Interviews
Equipment and Supplies

Keywords

  • closed-loop
  • deep brain stimulation
  • end-user perspectives
  • ethics
  • patient-controlled

ASJC Scopus subject areas

  • Human-Computer Interaction
  • Behavioral Neuroscience
  • Biomedical Engineering
  • Electrical and Electronic Engineering

Cite this

Brain-computer interface-based control of closed-loop brain stimulation : attitudes and ethical considerations. / Klein, Eran; Goering, Sara; Gagne, Josh; Shea, Conor V.; Franklin, Rachel; Zorowitz, Samuel; Dougherty, Darin D.; Widge, Alik S.

In: Brain-Computer Interfaces, Vol. 3, No. 3, 02.07.2016, p. 140-148.

Research output: Contribution to journalArticle

Klein, E, Goering, S, Gagne, J, Shea, CV, Franklin, R, Zorowitz, S, Dougherty, DD & Widge, AS 2016, 'Brain-computer interface-based control of closed-loop brain stimulation: attitudes and ethical considerations', Brain-Computer Interfaces, vol. 3, no. 3, pp. 140-148. https://doi.org/10.1080/2326263X.2016.1207497
Klein, Eran ; Goering, Sara ; Gagne, Josh ; Shea, Conor V. ; Franklin, Rachel ; Zorowitz, Samuel ; Dougherty, Darin D. ; Widge, Alik S. / Brain-computer interface-based control of closed-loop brain stimulation : attitudes and ethical considerations. In: Brain-Computer Interfaces. 2016 ; Vol. 3, No. 3. pp. 140-148.
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