Bone marrow transplantation from unrelated donors

James Gajewski, Richard Champlin

Research output: Contribution to journalReview articlepeer-review

10 Scopus citations

Abstract

Unrelated donor bone marrow transplants provide the alternative to allogeneic transplants for patients lacking an HLA-matched related family member donor. Because the donor and recipient have greater immunogenetic disparity than related donor transplants, these transplants are associated with a higher rate of immunologic complications. This disparity has also translated into a lower risk of relapse relative to sibling donor transplants, enabling this treatment to offer a cure to advanced-disease patients.

Original languageEnglish (US)
Pages (from-to)84-88
Number of pages5
JournalCurrent Opinion in Oncology
Volume8
Issue number2
DOIs
StatePublished - Jan 1 1996

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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