Bone marrow transplantation from unrelated donors

James Gajewski, Richard Champlin

    Research output: Contribution to journalReview article

    9 Scopus citations

    Abstract

    Unrelated donor bone marrow transplants provide the alternative to allogeneic transplants for patients lacking an HLA-matched related family member donor. Because the donor and recipient have greater immunogenetic disparity than related donor transplants, these transplants are associated with a higher rate of immunologic complications. This disparity has also translated into a lower risk of relapse relative to sibling donor transplants, enabling this treatment to offer a cure to advanced-disease patients.

    Original languageEnglish (US)
    Pages (from-to)84-88
    Number of pages5
    JournalCurrent Opinion in Oncology
    Volume8
    Issue number2
    DOIs
    StatePublished - Jan 1 1996

    ASJC Scopus subject areas

    • Oncology
    • Cancer Research

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