BNP or NTproBNP? A clinician's perspective

Johannes Steiner, Maya Guglin

Research output: Contribution to journalReview articlepeer-review

40 Scopus citations

Abstract

Existing literature on two natriuretic peptides - B-type natriuretic peptide (BNP) and amino terminal pro-brain natriuretic peptide (NTproBNP) - is overwhelming. Both peptides are acknowledged markers for cardiac dysfunction. Most of the sources present data on either BNP or NTproBNP making the comparison difficult. This paper focuses on reviewing studies directly comparing two peptides in the setting of chronic and acute heart failure (HF) and coronary artery disease. Many concomitant diseases influence these two peptides to varying extent. These characteristics should be taken into consideration when interpreting results. For most practical purposes, BNP and NTproBNP are interchangeable, and can be used based on local preferences and availability. NTproBNP seems to be more advantageous for diagnosing mild HF or asymptomatic left ventricular dysfunction.

Original languageEnglish (US)
Pages (from-to)5-14
Number of pages10
JournalInternational Journal of Cardiology
Volume129
Issue number1
DOIs
StatePublished - Sep 16 2008
Externally publishedYes

Keywords

  • BNP
  • Heart failure
  • NTproBNP
  • Natriuretic peptides

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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