Blood pressure and calcium intake are related to bone density in adult males

Jill A. Metz, Cynthia Morris, Leslie A. Roberts, Michael R. McClung, David A. McCarron

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

Based on the premise that elevated blood pressure and low bone mass have both been associated with poor Ca nutriture and disturbances in Ca metabolism, a cross-sectional study was employed to determine if blood pressure and dietary Ca intake were significantly related to bone mass. Forty-seven men between 24-77 years of age with blood pressure values ranging from normal to mildly elevated comprised the study group. Blood pressure was measured with a random-zero sphygmomanometer. Bone mineral content (BMC) and density (BMD) of the hip, spine and total body were measured with dual-photon absorptiometry. Dietary intake and physical activity were also assessed. Multiple linear regression analysis was used for statistical analysis. After adjusting for known confounding variables (age, BMI, Ca intake, and others) diastolic blood pressure was negatively related to BMC (P ≤ 0.05) and BMD (P ≤ 0.01) of the total body, trochanteric region (P <0.01) and Ward's triangle (P <0.05), and to BMC of the femoral neck (P <0.05) and lumbar spine, although the latter was just shy of statistical significance (P = 0.058). Systolic blood pressure was negatively related to trochanteric BMD (P = 0 04) and BMC (P = 0.06). Ca intake was positively related to total body BMD (P = 0.005), and BMC of the lumbar spine (P = 0.05). In this population of men, Ca intake was a positive predictor, and blood pressure was a negative predictor of regional measures of bone mass. These findings support the concept that independent of age, BMI and Ca intake, elevated blood pressure varies indirectly with bone mass and density, known predictors of osteoporotic fractures. Future studies are needed to determine whether elevated blood pressure is causally related to the development of low bone mass, and what role dietary Ca plays in that pathway.

Original languageEnglish (US)
Pages (from-to)383-388
Number of pages6
JournalBritish Journal of Nutrition
Volume81
Issue number5
StatePublished - 1999

Fingerprint

Bone Density
Blood Pressure
Calcium
Spine
Bone and Bones
Sphygmomanometers
Body Regions
Osteoporotic Fractures
Confounding Factors (Epidemiology)
Bone Development
Femur Neck
Photon Absorptiometry
Hypotension
Hip
Linear Models
Reference Values
Cross-Sectional Studies
Regression Analysis
Exercise

Keywords

  • Blood pressure
  • Bone mass
  • Calcium intake

ASJC Scopus subject areas

  • Medicine (miscellaneous)

Cite this

Metz, J. A., Morris, C., Roberts, L. A., McClung, M. R., & McCarron, D. A. (1999). Blood pressure and calcium intake are related to bone density in adult males. British Journal of Nutrition, 81(5), 383-388.

Blood pressure and calcium intake are related to bone density in adult males. / Metz, Jill A.; Morris, Cynthia; Roberts, Leslie A.; McClung, Michael R.; McCarron, David A.

In: British Journal of Nutrition, Vol. 81, No. 5, 1999, p. 383-388.

Research output: Contribution to journalArticle

Metz, JA, Morris, C, Roberts, LA, McClung, MR & McCarron, DA 1999, 'Blood pressure and calcium intake are related to bone density in adult males', British Journal of Nutrition, vol. 81, no. 5, pp. 383-388.
Metz, Jill A. ; Morris, Cynthia ; Roberts, Leslie A. ; McClung, Michael R. ; McCarron, David A. / Blood pressure and calcium intake are related to bone density in adult males. In: British Journal of Nutrition. 1999 ; Vol. 81, No. 5. pp. 383-388.
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