Biomarker testing to estimate under-reported heavy alcohol consumption by persons with HIV initiating ART in Uganda

Judith A. Hahn, Mwebesa B. Bwana, Martin A. Javors, Jeffrey N. Martin, Nneka I. Emenyonu, David Bangsberg

Research output: Contribution to journalArticle

21 Scopus citations

Abstract

Alcohol affects the transmission and treatment of HIV, yet may be under-reported in resource-limited settings. We compared self-reported alcohol consumption with levels of plasma carbohydrate-deficient transferrin (%CDT), a biomarker of heavy alcohol consumption, in persons initiating antiretroviral therapy in Uganda. Almost seven percent (6.7%) of persons reporting abstaining and 10% reporting consuming 1-40 drinks in the prior month tested positive for %CDT, and actual under-report may be higher due to low sensitivity of %CDT. These results suggest likely under-report in those reporting abstaining and current drinking. Improved identification of heavy alcohol consumption is needed for research and clinical purposes.

Original languageEnglish (US)
Pages (from-to)1265-1268
Number of pages4
JournalAIDS and Behavior
Volume14
Issue number6
DOIs
Publication statusPublished - 2010
Externally publishedYes

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Keywords

  • Alcohol drinking
  • Antiretroviral therapy
  • Biological markers
  • Carbohydrate-deficient transferrin
  • HIV
  • Uganda

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Infectious Diseases
  • Social Psychology

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