Biologically aggressive regions within glioblastoma identified by spin-lock contrast T1 relaxation in the rotating frame (T1ρ) MRI

Ramon Barajas, Javier Villanueva-Meyer, Arie Perry, Mitchel Berger, Soonmee Cha

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

Spin-lattice relaxation in the rotating frame magnetic resonance imaging allows for the quantitative assessment of spin-lock contrast within tissues. We describe the utility of spin-lattice relaxation in the rotating frame metrics in characterizing glioblastoma biological heterogeneity. A 84-year-old man presented to our institution with a right frontal temporal mass. Prior tissue sampling from a peripheral nonenhancing lesion was nondiagnostic. Stereotactic image-guided tissue sampling of the nonenhancing T2-fluid-attenuated inversion recovery hyperintense region involving the anterior cingulate gyrus with elevated spin-lattice relaxation in the rotating frame metrics provided a pathologic diagnosis of glioblastoma. This case illustrates the utility of spin-lattice relaxation in the rotating frame magnetic resonance imaging in identifying biologically aggressive regions within glioblastoma.

Original languageEnglish (US)
JournalRadiology Case Reports
DOIs
StateAccepted/In press - 2017

Keywords

  • Glioblastoma
  • Glioma
  • Image-guided
  • Spin-lock contrast
  • T1rho MRI
  • T1ρ MRI

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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