Bilateral cerebrovascular accidents in incontinentia pigmenti

Loretta Fiorillo, D. Barry Sinclair, Mary L. O'Byrne, Alfons L. Krol

Research output: Contribution to journalArticle

28 Scopus citations

Abstract

Incontinentia Pigmenti is an X-linked dominant neurocutaneous disorder with central nervous system manifestations in 30% of cases, including seizures and mental retardation. Ischemic or hemorrhagic cerebrovascular accidents have been reported rarely in incontinentia pigmenti. Chart review and literature search was performed following identification of the index case. We describe a patient with incontinentia pigmenti who developed bilateral cerebrovascular accidents in the neonatal period, with resultant severe neurologic sequelae. This is the second reported case of bilateral cerebrovascular accidents in a patient with incontinentia pigmenti. This finding may be secondary to cerebrovascular anomalies, similar to those observed in the retina. Recognition of cerebrovascular accidents as a complication of incontinentia pigmenti will hopefully lead to earlier recognition and treatment.

Original languageEnglish (US)
Pages (from-to)66-68
Number of pages3
JournalPediatric Neurology
Volume29
Issue number1
DOIs
StatePublished - Jul 2003

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Neurology
  • Developmental Neuroscience
  • Clinical Neurology

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