TY - JOUR
T1 - Beyond red hair and sunburns
T2 - Uncovering the molecular mechanisms of MC1R signaling and repair of UV-induced DNA damage
AU - Cassidy, Pamela B.
AU - Abdel-Malek, Zalfa A.
AU - Leachman, Sancy A.
N1 - Publisher Copyright:
© 2015 The Society for Investigative Dermatology.
PY - 2015/12/1
Y1 - 2015/12/1
N2 - Scientists at the University of Kentucky are unraveling the details of DNA-damage repair in the melanocyte, with an eye towards finding druggable targets for melanoma prevention. Jarret et al., (2015, this issue) report in this issue three new assays that can yield mechanistic information about nucleotide excision repair (NER) stimulated by cAMP-dependent signaling downstream of the melanocortin-1 receptor (MC1R).
AB - Scientists at the University of Kentucky are unraveling the details of DNA-damage repair in the melanocyte, with an eye towards finding druggable targets for melanoma prevention. Jarret et al., (2015, this issue) report in this issue three new assays that can yield mechanistic information about nucleotide excision repair (NER) stimulated by cAMP-dependent signaling downstream of the melanocortin-1 receptor (MC1R).
UR - http://www.scopus.com/inward/record.url?scp=84948701323&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84948701323&partnerID=8YFLogxK
U2 - 10.1038/jid.2015.349
DO - 10.1038/jid.2015.349
M3 - Comment/debate
C2 - 26569585
AN - SCOPUS:84948701323
SN - 0022-202X
VL - 135
SP - 2918
EP - 2921
JO - Journal of Investigative Dermatology
JF - Journal of Investigative Dermatology
IS - 12
ER -