Between-grader repeatability of tear meniscus measurements using fourier-domain OCT in patients with dry eye

Ethan H. Tittler, Matthew C. Bujak, Pho Nguyen, Xinbo Zhang, Yan Li, Samuel C. Yiu, David Huang

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

BACKGROUND AND OBJECTIVE: To examine the between-grader repeatability of height, depth, and cross-sectional area measurements of the lower tear meniscus, using a Fourier-domain optical coherence tomography (OCT) system. PATIENTS AND METHODS: A total of 16 patients with dry eye had the lower tear meniscus of the right eye imaged twice in rapid succession. The tear meniscus height, depth, and cross-sectional area were measured by two masked graders using computer calipers. The between-grader variability, calculated using the pooled coefficient of variation (CV%), assessed the repeatability of the measurements. RESULTS: The between-grader CV% was 12.1%, 15.7%, and 19.5% for height, depth, and area, respectively. The between-image variability was 17.1%, 13.4%, and 35.4% for height, depth, and area, respectively. The overall intraclass correlation was 99%. There was no systematic bias between the two graders. CONCLUSION: Fourier-domain OCT demonstrates good between-grader and between-image repeatability in measuring the height, depth, and cross-sectional area of the tear meniscus in patients with dry eye. Measurement variability was primarily due to the difference between images rather than graders.

Original languageEnglish (US)
Pages (from-to)423-427
Number of pages5
JournalOphthalmic Surgery Lasers and Imaging
Volume42
Issue number5
DOIs
StatePublished - Sep 2011
Externally publishedYes

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Optical Coherence Tomography
Tears
Meniscus

ASJC Scopus subject areas

  • Ophthalmology
  • Surgery

Cite this

Between-grader repeatability of tear meniscus measurements using fourier-domain OCT in patients with dry eye. / Tittler, Ethan H.; Bujak, Matthew C.; Nguyen, Pho; Zhang, Xinbo; Li, Yan; Yiu, Samuel C.; Huang, David.

In: Ophthalmic Surgery Lasers and Imaging, Vol. 42, No. 5, 09.2011, p. 423-427.

Research output: Contribution to journalArticle

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AU - Yiu, Samuel C.

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