TY - JOUR
T1 - Benign and malignant tumor stages in a mouse keratinocyte line treated with 7,12-dimethylbenz[a]anthracene in vitro
AU - Kulesz-Martin, Molly F.
AU - Penetrante, Remedios
AU - East, Christopher J.
N1 - Funding Information:
The authors are grateful to Mrs Barbara Lisafeld and Ms Jo Ellen Budnick for technical assistance, Dr James E.Strickland, (NCI, Bethesda, MD) for helpful discussion, Ms Mae Brown for typing, Mr George Fox for photography and Ms Ruth Weaver for histology. This investigation was supported by PHS grant numbers CA-31101 and CA-24538 awarded by The National Cancer Institute. All animal protocols were approved by the Roswell Park Memorial Institute Animal Care and Utilization Committee.
PY - 1988/1
Y1 - 1988/1
N2 - Stable pre-tumorigenic, benign tumor and squamous cell carcinoma stages have been isolated after treatment of a cloned mouse keratinocyte line with 7,12-dimethylbenz[a]anthracene. Intraperitoneal injection and skin grafting of athymic nude mice were suitable for growth of these well-differentiated tumor cells, whereas subcutaneous injection was not.
AB - Stable pre-tumorigenic, benign tumor and squamous cell carcinoma stages have been isolated after treatment of a cloned mouse keratinocyte line with 7,12-dimethylbenz[a]anthracene. Intraperitoneal injection and skin grafting of athymic nude mice were suitable for growth of these well-differentiated tumor cells, whereas subcutaneous injection was not.
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U2 - 10.1093/carcin/9.1.171
DO - 10.1093/carcin/9.1.171
M3 - Article
C2 - 2446796
AN - SCOPUS:0013664647
SN - 0143-3334
VL - 9
SP - 171
EP - 174
JO - Carcinogenesis
JF - Carcinogenesis
IS - 1
ER -