Benign and malignant tumor stages in a mouse keratinocyte line treated with 7,12-dimethylbenz[a]anthracene in vitro

Molly F. Kulesz-Martin, Remedios Penetrante, Christopher J. East

Research output: Contribution to journalArticle

28 Scopus citations

Abstract

Stable pre-tumorigenic, benign tumor and squamous cell carcinoma stages have been isolated after treatment of a cloned mouse keratinocyte line with 7,12-dimethylbenz[a]anthracene. Intraperitoneal injection and skin grafting of athymic nude mice were suitable for growth of these well-differentiated tumor cells, whereas subcutaneous injection was not.

Original languageEnglish (US)
Pages (from-to)171-174
Number of pages4
JournalCarcinogenesis
Volume9
Issue number1
DOIs
StatePublished - Jan 1 1988

ASJC Scopus subject areas

  • Cancer Research

Fingerprint Dive into the research topics of 'Benign and malignant tumor stages in a mouse keratinocyte line treated with 7,12-dimethylbenz[a]anthracene in vitro'. Together they form a unique fingerprint.

Cite this