Behavioral interventions for reducing head motion during MRI scans in children

Deanna J. Greene, Jonathan M. Koller, Jacqueline M. Hampton, Victoria Wesevich, Andrew N. Van, Annie L. Nguyen, Catherine R. Hoyt, Lindsey McIntyre, Eric A. Earl, Rachel L. Klein, Joshua S. Shimony, Steven E. Petersen, Bradley L. Schlaggar, Damien Fair, Nico U.F. Dosenbach

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

A major limitation to structural and functional MRI (fMRI) scans is their susceptibility to head motion artifacts. Even submillimeter movements can systematically distort functional connectivity, morphometric, and diffusion imaging results. In patient care, sedation is often used to minimize head motion, but it incurs increased costs and risks. In research settings, sedation is typically not an ethical option. Therefore, safe methods that reduce head motion are critical for improving MRI quality, especially in high movement individuals such as children and neuropsychiatric patients. We investigated the effects of (1) viewing movies and (2) receiving real-time visual feedback about head movement in 24 children (5–15 years old). Children completed fMRI scans during which they viewed a fixation cross (i.e., rest) or a cartoon movie clip, and during some of the scans they also received real-time visual feedback about head motion. Head motion was significantly reduced during movie watching compared to rest and when receiving feedback compared to receiving no feedback. However, these results depended on age, such that the effects were largely driven by the younger children. Children older than 10 years showed no significant benefit. We also found that viewing movies significantly altered the functional connectivity of fMRI data, suggesting that fMRI scans during movies cannot be equated to standard resting-state fMRI scans. The implications of these results are twofold: (1) given the reduction in head motion with behavioral interventions, these methods should be tried first for all clinical and structural MRIs in lieu of sedation; and (2) for fMRI research scans, these methods can reduce head motion in certain groups, but investigators must keep in mind the effects on functional MRI data.

Original languageEnglish (US)
Pages (from-to)234-245
Number of pages12
JournalNeuroImage
Volume171
DOIs
StatePublished - May 1 2018

Fingerprint

Head
Magnetic Resonance Imaging
Motion Pictures
Sensory Feedback
Cartoons
Head Movements
Research
Surgical Instruments
Artifacts
Patient Care
Research Personnel
Costs and Cost Analysis

Keywords

  • Development
  • Feedback
  • Motion
  • Movies
  • MRI
  • Resting state

ASJC Scopus subject areas

  • Neurology
  • Cognitive Neuroscience

Cite this

Greene, D. J., Koller, J. M., Hampton, J. M., Wesevich, V., Van, A. N., Nguyen, A. L., ... Dosenbach, N. U. F. (2018). Behavioral interventions for reducing head motion during MRI scans in children. NeuroImage, 171, 234-245. https://doi.org/10.1016/j.neuroimage.2018.01.023

Behavioral interventions for reducing head motion during MRI scans in children. / Greene, Deanna J.; Koller, Jonathan M.; Hampton, Jacqueline M.; Wesevich, Victoria; Van, Andrew N.; Nguyen, Annie L.; Hoyt, Catherine R.; McIntyre, Lindsey; Earl, Eric A.; Klein, Rachel L.; Shimony, Joshua S.; Petersen, Steven E.; Schlaggar, Bradley L.; Fair, Damien; Dosenbach, Nico U.F.

In: NeuroImage, Vol. 171, 01.05.2018, p. 234-245.

Research output: Contribution to journalArticle

Greene, DJ, Koller, JM, Hampton, JM, Wesevich, V, Van, AN, Nguyen, AL, Hoyt, CR, McIntyre, L, Earl, EA, Klein, RL, Shimony, JS, Petersen, SE, Schlaggar, BL, Fair, D & Dosenbach, NUF 2018, 'Behavioral interventions for reducing head motion during MRI scans in children', NeuroImage, vol. 171, pp. 234-245. https://doi.org/10.1016/j.neuroimage.2018.01.023
Greene DJ, Koller JM, Hampton JM, Wesevich V, Van AN, Nguyen AL et al. Behavioral interventions for reducing head motion during MRI scans in children. NeuroImage. 2018 May 1;171:234-245. https://doi.org/10.1016/j.neuroimage.2018.01.023
Greene, Deanna J. ; Koller, Jonathan M. ; Hampton, Jacqueline M. ; Wesevich, Victoria ; Van, Andrew N. ; Nguyen, Annie L. ; Hoyt, Catherine R. ; McIntyre, Lindsey ; Earl, Eric A. ; Klein, Rachel L. ; Shimony, Joshua S. ; Petersen, Steven E. ; Schlaggar, Bradley L. ; Fair, Damien ; Dosenbach, Nico U.F. / Behavioral interventions for reducing head motion during MRI scans in children. In: NeuroImage. 2018 ; Vol. 171. pp. 234-245.
@article{668cd5d7cab34c62a507d7306127898c,
title = "Behavioral interventions for reducing head motion during MRI scans in children",
abstract = "A major limitation to structural and functional MRI (fMRI) scans is their susceptibility to head motion artifacts. Even submillimeter movements can systematically distort functional connectivity, morphometric, and diffusion imaging results. In patient care, sedation is often used to minimize head motion, but it incurs increased costs and risks. In research settings, sedation is typically not an ethical option. Therefore, safe methods that reduce head motion are critical for improving MRI quality, especially in high movement individuals such as children and neuropsychiatric patients. We investigated the effects of (1) viewing movies and (2) receiving real-time visual feedback about head movement in 24 children (5–15 years old). Children completed fMRI scans during which they viewed a fixation cross (i.e., rest) or a cartoon movie clip, and during some of the scans they also received real-time visual feedback about head motion. Head motion was significantly reduced during movie watching compared to rest and when receiving feedback compared to receiving no feedback. However, these results depended on age, such that the effects were largely driven by the younger children. Children older than 10 years showed no significant benefit. We also found that viewing movies significantly altered the functional connectivity of fMRI data, suggesting that fMRI scans during movies cannot be equated to standard resting-state fMRI scans. The implications of these results are twofold: (1) given the reduction in head motion with behavioral interventions, these methods should be tried first for all clinical and structural MRIs in lieu of sedation; and (2) for fMRI research scans, these methods can reduce head motion in certain groups, but investigators must keep in mind the effects on functional MRI data.",
keywords = "Development, Feedback, Motion, Movies, MRI, Resting state",
author = "Greene, {Deanna J.} and Koller, {Jonathan M.} and Hampton, {Jacqueline M.} and Victoria Wesevich and Van, {Andrew N.} and Nguyen, {Annie L.} and Hoyt, {Catherine R.} and Lindsey McIntyre and Earl, {Eric A.} and Klein, {Rachel L.} and Shimony, {Joshua S.} and Petersen, {Steven E.} and Schlaggar, {Bradley L.} and Damien Fair and Dosenbach, {Nico U.F.}",
year = "2018",
month = "5",
day = "1",
doi = "10.1016/j.neuroimage.2018.01.023",
language = "English (US)",
volume = "171",
pages = "234--245",
journal = "NeuroImage",
issn = "1053-8119",
publisher = "Academic Press Inc.",

}

TY - JOUR

T1 - Behavioral interventions for reducing head motion during MRI scans in children

AU - Greene, Deanna J.

AU - Koller, Jonathan M.

AU - Hampton, Jacqueline M.

AU - Wesevich, Victoria

AU - Van, Andrew N.

AU - Nguyen, Annie L.

AU - Hoyt, Catherine R.

AU - McIntyre, Lindsey

AU - Earl, Eric A.

AU - Klein, Rachel L.

AU - Shimony, Joshua S.

AU - Petersen, Steven E.

AU - Schlaggar, Bradley L.

AU - Fair, Damien

AU - Dosenbach, Nico U.F.

PY - 2018/5/1

Y1 - 2018/5/1

N2 - A major limitation to structural and functional MRI (fMRI) scans is their susceptibility to head motion artifacts. Even submillimeter movements can systematically distort functional connectivity, morphometric, and diffusion imaging results. In patient care, sedation is often used to minimize head motion, but it incurs increased costs and risks. In research settings, sedation is typically not an ethical option. Therefore, safe methods that reduce head motion are critical for improving MRI quality, especially in high movement individuals such as children and neuropsychiatric patients. We investigated the effects of (1) viewing movies and (2) receiving real-time visual feedback about head movement in 24 children (5–15 years old). Children completed fMRI scans during which they viewed a fixation cross (i.e., rest) or a cartoon movie clip, and during some of the scans they also received real-time visual feedback about head motion. Head motion was significantly reduced during movie watching compared to rest and when receiving feedback compared to receiving no feedback. However, these results depended on age, such that the effects were largely driven by the younger children. Children older than 10 years showed no significant benefit. We also found that viewing movies significantly altered the functional connectivity of fMRI data, suggesting that fMRI scans during movies cannot be equated to standard resting-state fMRI scans. The implications of these results are twofold: (1) given the reduction in head motion with behavioral interventions, these methods should be tried first for all clinical and structural MRIs in lieu of sedation; and (2) for fMRI research scans, these methods can reduce head motion in certain groups, but investigators must keep in mind the effects on functional MRI data.

AB - A major limitation to structural and functional MRI (fMRI) scans is their susceptibility to head motion artifacts. Even submillimeter movements can systematically distort functional connectivity, morphometric, and diffusion imaging results. In patient care, sedation is often used to minimize head motion, but it incurs increased costs and risks. In research settings, sedation is typically not an ethical option. Therefore, safe methods that reduce head motion are critical for improving MRI quality, especially in high movement individuals such as children and neuropsychiatric patients. We investigated the effects of (1) viewing movies and (2) receiving real-time visual feedback about head movement in 24 children (5–15 years old). Children completed fMRI scans during which they viewed a fixation cross (i.e., rest) or a cartoon movie clip, and during some of the scans they also received real-time visual feedback about head motion. Head motion was significantly reduced during movie watching compared to rest and when receiving feedback compared to receiving no feedback. However, these results depended on age, such that the effects were largely driven by the younger children. Children older than 10 years showed no significant benefit. We also found that viewing movies significantly altered the functional connectivity of fMRI data, suggesting that fMRI scans during movies cannot be equated to standard resting-state fMRI scans. The implications of these results are twofold: (1) given the reduction in head motion with behavioral interventions, these methods should be tried first for all clinical and structural MRIs in lieu of sedation; and (2) for fMRI research scans, these methods can reduce head motion in certain groups, but investigators must keep in mind the effects on functional MRI data.

KW - Development

KW - Feedback

KW - Motion

KW - Movies

KW - MRI

KW - Resting state

UR - http://www.scopus.com/inward/record.url?scp=85042937814&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85042937814&partnerID=8YFLogxK

U2 - 10.1016/j.neuroimage.2018.01.023

DO - 10.1016/j.neuroimage.2018.01.023

M3 - Article

C2 - 29337280

AN - SCOPUS:85042937814

VL - 171

SP - 234

EP - 245

JO - NeuroImage

JF - NeuroImage

SN - 1053-8119

ER -