Beaned: Fatal forty DDI: Diltiazem, tacrolimus, CYP3A4, P-glycoprotein

Matthew Hart, Michael Hutchens

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

This case discusses the pharmacokinetic interaction of tacrolimus and diltiazem, including to tacrolimus toxicity. Tacrolimus is a cytochrome P450 3A4 and intestinal P-glycoprotein substrate and diltiazem is an inhibitor.

Original languageEnglish (US)
Title of host publicationA Case Approach to Perioperative Drug-Drug Interactions
PublisherSpringer New York
Pages693-695
Number of pages3
ISBN (Electronic)9781461474951
ISBN (Print)9781461474944
DOIs
Publication statusPublished - Sep 15 2015

    Fingerprint

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Hart, M., & Hutchens, M. (2015). Beaned: Fatal forty DDI: Diltiazem, tacrolimus, CYP3A4, P-glycoprotein. In A Case Approach to Perioperative Drug-Drug Interactions (pp. 693-695). Springer New York. https://doi.org/10.1007/978-1-4614-7495-1_154