@article{a5c9ae9eaa9a4e32a2b2ae3c78c1e559,
title = "Baricitinib treatment resolves lower-airway macrophage inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaques",
abstract = "Using a rhesus macaque infection model, it is shown that baricitinib treatment started early after infection effectively resolves inflammatory signatures in airway macrophages, with decreased lung pathology and neutrophil infiltration.",
keywords = "COVID-19, SARS-CoV-2, baricitinib, immune activation, immunology, inflammation, nonhuman primate, pathogenesis",
author = "Hoang, {Timothy N.} and Maria Pino and Boddapati, {Arun K.} and Viox, {Elise G.} and Starke, {Carly E.} and Upadhyay, {Amit A.} and Sanjeev Gumber and Michael Nekorchuk and Kathleen Busman-Sahay and Zachary Strongin and Harper, {Justin L.} and Tharp, {Gregory K.} and Pellegrini, {Kathryn L.} and Shannon Kirejczyk and Keivan Zandi and Sijia Tao and Horton, {Tristan R.} and Beagle, {Elizabeth N.} and Mahar, {Ernestine A.} and Lee, {Michelle Y.H.} and Joyce Cohen and Jean, {Sherrie M.} and Wood, {Jennifer S.} and Fawn Connor-Stroud and Stammen, {Rachelle L.} and Delmas, {Olivia M.} and Shelly Wang and Cooney, {Kimberly A.} and Sayegh, {Michael N.} and Lanfang Wang and Filev, {Peter D.} and Daniela Weiskopf and Guido Silvestri and Jesse Waggoner and Anne Piantadosi and Kasturi, {Sudhir P.} and Hilmi Al-Shakhshir and Ribeiro, {Susan P.} and Sekaly, {Rafick P.} and Levit, {Rebecca D.} and Estes, {Jacob D.} and Vanderford, {Thomas H.} and Schinazi, {Raymond F.} and Bosinger, {Steven E.} and Mirko Paiardini",
note = "Publisher Copyright: {\textcopyright} 2020 Elsevier Inc.",
year = "2021",
month = jan,
day = "21",
doi = "10.1016/j.cell.2020.11.007",
language = "English (US)",
volume = "184",
pages = "460--475.e21",
journal = "Cell",
issn = "0092-8674",
publisher = "Cell Press",
number = "2",
}