Axon Degeneration: Too Much NMN Is Actually Bad?

Research output: Contribution to journalShort survey

Abstract

The mechanism of axon degeneration is incompletely understood. A recent study demonstrates that transgenic expression of bacterial nicotinamide adenine mononucleotide (NMN) in zebrafish and mice, which decreases NMN levels by converting it to NaMN, protects against axon degeneration.

Original languageEnglish (US)
Pages (from-to)R310-R312
JournalCurrent Biology
Volume27
Issue number8
DOIs
StatePublished - Apr 24 2017

Fingerprint

axons
Axons
Nicotinamide Mononucleotide
nicotinamide
Niacinamide
Zebrafish
Adenine
adenine
Danio rerio
gene expression
mice

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)

Cite this

Axon Degeneration : Too Much NMN Is Actually Bad? / Cohen, Michael.

In: Current Biology, Vol. 27, No. 8, 24.04.2017, p. R310-R312.

Research output: Contribution to journalShort survey

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