Autonomic dysfunction in Parkinson's disease: A comprehensive symptom survey

M. F. Siddiqui, S. Rast, M. J. Lynn, A. P. Auchus, Ronald Pfeiffer

Research output: Contribution to journalArticle

131 Citations (Scopus)

Abstract

Background: Autonomic dysfunction occurs in Parkinson's disease (PD), but few studies have addressed it in a comprehensive manner. Methods: Autonomic symptoms were evaluated by a questionnaire in sixty-eight subjects (44 patients and 24 controls). Results: PD patients experienced higher frequency and severity of autonomic dysfunction. When all autonomic symptoms were pooled into an aggregate score, differences between patients and controls were highly statistically significant (p <0.0001). 'Increased salivation', 'frequency of dysphagia', decreased 'BM (bowel movement) frequency', i.e. constipation, and 'orthostatic dizziness' were more frequent in PD patients (p <0.05). A prediction model to determine the predictors of autonomic dysfunction was unsuccessful. Conclusion: Differences in the prevalence of autonomic symptoms in PD and non-parkinsonian controls are apparent from this study.

Original languageEnglish (US)
Pages (from-to)277-284
Number of pages8
JournalParkinsonism and Related Disorders
Volume8
Issue number4
DOIs
StatePublished - 2002
Externally publishedYes

Fingerprint

Parkinson Disease
Salivation
Dizziness
Constipation
Deglutition Disorders
Surveys and Questionnaires

Keywords

  • Autonomic function
  • Multiple system atrophy
  • Parkinson's disease

ASJC Scopus subject areas

  • Aging
  • Clinical Neurology
  • Neurology

Cite this

Autonomic dysfunction in Parkinson's disease : A comprehensive symptom survey. / Siddiqui, M. F.; Rast, S.; Lynn, M. J.; Auchus, A. P.; Pfeiffer, Ronald.

In: Parkinsonism and Related Disorders, Vol. 8, No. 4, 2002, p. 277-284.

Research output: Contribution to journalArticle

Siddiqui, M. F. ; Rast, S. ; Lynn, M. J. ; Auchus, A. P. ; Pfeiffer, Ronald. / Autonomic dysfunction in Parkinson's disease : A comprehensive symptom survey. In: Parkinsonism and Related Disorders. 2002 ; Vol. 8, No. 4. pp. 277-284.
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