TY - GEN
T1 - Automated head motion system improves reliability and lessens operator dependence for head impulse testing of vestibular reflexes
AU - Tan, Grace X.
AU - Schoo, Desi P.
AU - Santina, Charles C.Della
AU - Rahman, Mehdi A.
AU - Valentin Contreras, Nicolas S.
AU - Sun, Chen Hsin
AU - Chiang, Bryce
N1 - Publisher Copyright:
© 2017 IEEE.
PY - 2017/7/19
Y1 - 2017/7/19
N2 - Deficiency of the eye-stabilizing vestibulo-ocular reflex (VOR) is a defining feature in multiple diseases of the vestibular labyrinth, which comprises the inner ear's sensors of head rotation, translation and orientation. Diagnosis of these disorders is facilitated by observation and measurement of eye movements during and after head motion. The video head impulse test has recently garnered interest as a clinical diagnostic assessment of vestibular dysfunction. In typical practice, it involves use of video-oculography goggles to measure eye movements while a clinician examiner grasps the subject's head and manually rotates it left or right at sufficient acceleration to cover ∼20 deg over ∼150 mS, reaching a peak velocity of >120 deg/S midway through the movement. Manual delivery of head impulses incurs significant trial-by-trial, inter-session and interoperator variability, which lessens the test's reliability, efficiency, safety and standardization across testing facilities. We describe application of a novel, compact and portable automated head impulse test (aHIT™) device that delivers highly repeatable head motion stimuli about axes parallel to those of the vestibular labyrinth's six semicircular canals, with programmable Gaussian and sinusoidal motion profiles at amplitudes, velocities and accelerations sufficient to test VOR function over the spectral range for which the VOR dominates other vision-stabilizing reflexes. We tested the aHIT™ on human subjects and demonstrated its high reproducibility compared to manually delivered head impulses. This device has the potential to be a valuable clinical and research tool for diagnostic evaluation and investigation of the vestibular system.
AB - Deficiency of the eye-stabilizing vestibulo-ocular reflex (VOR) is a defining feature in multiple diseases of the vestibular labyrinth, which comprises the inner ear's sensors of head rotation, translation and orientation. Diagnosis of these disorders is facilitated by observation and measurement of eye movements during and after head motion. The video head impulse test has recently garnered interest as a clinical diagnostic assessment of vestibular dysfunction. In typical practice, it involves use of video-oculography goggles to measure eye movements while a clinician examiner grasps the subject's head and manually rotates it left or right at sufficient acceleration to cover ∼20 deg over ∼150 mS, reaching a peak velocity of >120 deg/S midway through the movement. Manual delivery of head impulses incurs significant trial-by-trial, inter-session and interoperator variability, which lessens the test's reliability, efficiency, safety and standardization across testing facilities. We describe application of a novel, compact and portable automated head impulse test (aHIT™) device that delivers highly repeatable head motion stimuli about axes parallel to those of the vestibular labyrinth's six semicircular canals, with programmable Gaussian and sinusoidal motion profiles at amplitudes, velocities and accelerations sufficient to test VOR function over the spectral range for which the VOR dominates other vision-stabilizing reflexes. We tested the aHIT™ on human subjects and demonstrated its high reproducibility compared to manually delivered head impulses. This device has the potential to be a valuable clinical and research tool for diagnostic evaluation and investigation of the vestibular system.
KW - aHIT
KW - automated head impulse test
KW - head impulse test
KW - vestibular system
KW - vestibulo-ocular reflex
UR - http://www.scopus.com/inward/record.url?scp=85027876549&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85027876549&partnerID=8YFLogxK
U2 - 10.1109/MeMeA.2017.7985856
DO - 10.1109/MeMeA.2017.7985856
M3 - Conference contribution
AN - SCOPUS:85027876549
T3 - 2017 IEEE International Symposium on Medical Measurements and Applications, MeMeA 2017 - Proceedings
SP - 94
EP - 99
BT - 2017 IEEE International Symposium on Medical Measurements and Applications, MeMeA 2017 - Proceedings
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 12th IEEE International Symposium on Medical Measurements and Applications, MeMeA 2017
Y2 - 7 May 2017 through 10 May 2017
ER -