Auditory brainstem response differences in diabetic and non-diabetic veterans

Nancy Vaughan, Kenneth James, Daniel McDermott, Susan Griest, Stephen Fausti

Research output: Contribution to journalArticle

16 Scopus citations

Abstract

A number of studies have found statistically significant delays in auditory brainstem latencies of patients with diabetes compared with non-diabetic controls. However, the mechanisms ascribed as responsible for the latency differences between diabetic and non-diabetic patients vary among studies, and the latency differences, while significant, are small. In this 5-year prospective study, auditory brainstem response testing was conducted with 416 non-diabetic and 375 diabetic veterans from the Portland Veterans Affairs Medical Center as part of a larger study. Patients with diabetes had significantly delayed latencies of Wave III and V in the right ear and significantly prolonged interpeak I-III and I-V latencies in both ears. Stimulus polarity difference yielded slightly different results. None of the diabetes-related clinical characteristics were associated with the latency differences between the subject groups after accounting for hearing loss and age. Effect size was calculated and clinical significance of these differences is discussed.

Original languageEnglish (US)
Pages (from-to)863-871
Number of pages9
JournalJournal of the American Academy of Audiology
Volume18
Issue number10
DOIs
StatePublished - Nov 1 2007

Keywords

  • Auditory brainstem response
  • Diabetes
  • Latency
  • Neuropathy

ASJC Scopus subject areas

  • Speech and Hearing

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