Astrocytic hamartoma in tuberous sclerosis mimicking necrotizing retinochoroiditis

J. R. Coppeto, J. R. Lubin, Daniel Albert

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

A pale, elevated peripapillary lesion discovered in a young child with no family history of phakomatoses, grew larger, caused vitreous hemorrhage and underwent necrosis. Secondary inflammation developed in the eye, finally producing rubeosis irides with elevated intraocular pressure and a blind, painful eye which required enucleation. Clinically, the lesion was variably diagnosed and treated as toxoplasmosis and Toxocara canis. These diagnoses were made despite low titres, a negative ELISA test and a normal eosinophil count. On histopathologic examination, a diagnosis of Toxocara canis was entertained, although no remnants of the organism could be found in serial sections. Years later, when a family history of tuberous sclerosis became apparent, a diagnosis of astrocytic hamartoma of the retina with secondary hemorrhage and inflammation was made on the basis of reexamination of the pathologic specimen and special stains.

Original languageEnglish (US)
Pages (from-to)306-313
Number of pages8
JournalJournal of pediatric ophthalmology and strabismus
Volume19
Issue number6
StatePublished - Dec 1 1982
Externally publishedYes

Fingerprint

Tuberous Sclerosis
Hamartoma
Toxocara canis
Neurocutaneous Syndromes
Inflammation
Vitreous Hemorrhage
Toxoplasmosis
Iris
Intraocular Pressure
Eosinophils
Retina
Necrosis
Coloring Agents
Enzyme-Linked Immunosorbent Assay
Hemorrhage

ASJC Scopus subject areas

  • Ophthalmology
  • Pediatrics, Perinatology, and Child Health

Cite this

Astrocytic hamartoma in tuberous sclerosis mimicking necrotizing retinochoroiditis. / Coppeto, J. R.; Lubin, J. R.; Albert, Daniel.

In: Journal of pediatric ophthalmology and strabismus, Vol. 19, No. 6, 01.12.1982, p. 306-313.

Research output: Contribution to journalArticle

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