Associations of childhood eczema severity: A US population-based study

Jonathan I. Silverberg, Eric Simpson

Research output: Contribution to journalArticle

76 Citations (Scopus)

Abstract

Background: Little is known about the predictors of eczema severity in the US population. Objectives: We sought to determine the distribution and associations of childhood eczema severity in theUnitedStates. Methods: We analyzed the data from the 2007 National Survey of Children's Health, a prospective questionnairebased study of a nationally representative sample of 91,642 children (range, 0Y17 years). Results: The prevalence of childhood eczema was 12.97% (95% confidence interval [95% CI], 12.42Y13.53); 67.0% (95% CI, 64.8Y69.2) had mild disease, 26.0% (95% CI, 23.9Y28.1) had moderate disease, and 7.0% (95% CI, 5.8Y8.3) had severe disease. There was significant statewide variation of the distribution of eczema severity (Rao-Scott W2, P = 0.004), with highest rates of severe disease in Mid-Atlantic and Midwestern states. In univariate models, eczema severity was increased with older age, African American and Hispanic race/ethnicity, lower household income, oldest child in the family, home with a single mother, lower paternal/maternal education level, maternal general health, maternal/paternal emotional health, dilapidated housing, and garbage on the streets. In multivariate survey logistic regression models using stepwise and backward selection, moderate-to-severe eczema was associated with older age, lower household income, and fair or poor maternal health but inversely associated with birthplace outside the United States. Conclusions: These data indicate that environmental and/or lifestyle factors play an important role in eczema severity.

Original languageEnglish (US)
Pages (from-to)107-114
Number of pages8
JournalDermatitis
Volume25
Issue number3
DOIs
StatePublished - 2014

Fingerprint

Eczema
Population
Confidence Intervals
Mothers
Logistic Models
Garbage
Hispanic Americans
African Americans
Life Style
Prospective Studies
Education
Health

ASJC Scopus subject areas

  • Dermatology
  • Immunology and Allergy
  • Medicine(all)

Cite this

Associations of childhood eczema severity : A US population-based study. / Silverberg, Jonathan I.; Simpson, Eric.

In: Dermatitis, Vol. 25, No. 3, 2014, p. 107-114.

Research output: Contribution to journalArticle

Silverberg, Jonathan I. ; Simpson, Eric. / Associations of childhood eczema severity : A US population-based study. In: Dermatitis. 2014 ; Vol. 25, No. 3. pp. 107-114.
@article{2df9cf24a9b04e94a357f0a45405f28a,
title = "Associations of childhood eczema severity: A US population-based study",
abstract = "Background: Little is known about the predictors of eczema severity in the US population. Objectives: We sought to determine the distribution and associations of childhood eczema severity in theUnitedStates. Methods: We analyzed the data from the 2007 National Survey of Children's Health, a prospective questionnairebased study of a nationally representative sample of 91,642 children (range, 0Y17 years). Results: The prevalence of childhood eczema was 12.97{\%} (95{\%} confidence interval [95{\%} CI], 12.42Y13.53); 67.0{\%} (95{\%} CI, 64.8Y69.2) had mild disease, 26.0{\%} (95{\%} CI, 23.9Y28.1) had moderate disease, and 7.0{\%} (95{\%} CI, 5.8Y8.3) had severe disease. There was significant statewide variation of the distribution of eczema severity (Rao-Scott W2, P = 0.004), with highest rates of severe disease in Mid-Atlantic and Midwestern states. In univariate models, eczema severity was increased with older age, African American and Hispanic race/ethnicity, lower household income, oldest child in the family, home with a single mother, lower paternal/maternal education level, maternal general health, maternal/paternal emotional health, dilapidated housing, and garbage on the streets. In multivariate survey logistic regression models using stepwise and backward selection, moderate-to-severe eczema was associated with older age, lower household income, and fair or poor maternal health but inversely associated with birthplace outside the United States. Conclusions: These data indicate that environmental and/or lifestyle factors play an important role in eczema severity.",
author = "Silverberg, {Jonathan I.} and Eric Simpson",
year = "2014",
doi = "10.1097/DER.0000000000000034",
language = "English (US)",
volume = "25",
pages = "107--114",
journal = "Dermatitis : contact, atopic, occupational, drug",
issn = "1710-3568",
publisher = "Decker Publishing",
number = "3",

}

TY - JOUR

T1 - Associations of childhood eczema severity

T2 - A US population-based study

AU - Silverberg, Jonathan I.

AU - Simpson, Eric

PY - 2014

Y1 - 2014

N2 - Background: Little is known about the predictors of eczema severity in the US population. Objectives: We sought to determine the distribution and associations of childhood eczema severity in theUnitedStates. Methods: We analyzed the data from the 2007 National Survey of Children's Health, a prospective questionnairebased study of a nationally representative sample of 91,642 children (range, 0Y17 years). Results: The prevalence of childhood eczema was 12.97% (95% confidence interval [95% CI], 12.42Y13.53); 67.0% (95% CI, 64.8Y69.2) had mild disease, 26.0% (95% CI, 23.9Y28.1) had moderate disease, and 7.0% (95% CI, 5.8Y8.3) had severe disease. There was significant statewide variation of the distribution of eczema severity (Rao-Scott W2, P = 0.004), with highest rates of severe disease in Mid-Atlantic and Midwestern states. In univariate models, eczema severity was increased with older age, African American and Hispanic race/ethnicity, lower household income, oldest child in the family, home with a single mother, lower paternal/maternal education level, maternal general health, maternal/paternal emotional health, dilapidated housing, and garbage on the streets. In multivariate survey logistic regression models using stepwise and backward selection, moderate-to-severe eczema was associated with older age, lower household income, and fair or poor maternal health but inversely associated with birthplace outside the United States. Conclusions: These data indicate that environmental and/or lifestyle factors play an important role in eczema severity.

AB - Background: Little is known about the predictors of eczema severity in the US population. Objectives: We sought to determine the distribution and associations of childhood eczema severity in theUnitedStates. Methods: We analyzed the data from the 2007 National Survey of Children's Health, a prospective questionnairebased study of a nationally representative sample of 91,642 children (range, 0Y17 years). Results: The prevalence of childhood eczema was 12.97% (95% confidence interval [95% CI], 12.42Y13.53); 67.0% (95% CI, 64.8Y69.2) had mild disease, 26.0% (95% CI, 23.9Y28.1) had moderate disease, and 7.0% (95% CI, 5.8Y8.3) had severe disease. There was significant statewide variation of the distribution of eczema severity (Rao-Scott W2, P = 0.004), with highest rates of severe disease in Mid-Atlantic and Midwestern states. In univariate models, eczema severity was increased with older age, African American and Hispanic race/ethnicity, lower household income, oldest child in the family, home with a single mother, lower paternal/maternal education level, maternal general health, maternal/paternal emotional health, dilapidated housing, and garbage on the streets. In multivariate survey logistic regression models using stepwise and backward selection, moderate-to-severe eczema was associated with older age, lower household income, and fair or poor maternal health but inversely associated with birthplace outside the United States. Conclusions: These data indicate that environmental and/or lifestyle factors play an important role in eczema severity.

UR - http://www.scopus.com/inward/record.url?scp=84902650535&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84902650535&partnerID=8YFLogxK

U2 - 10.1097/DER.0000000000000034

DO - 10.1097/DER.0000000000000034

M3 - Article

C2 - 24819283

AN - SCOPUS:84902650535

VL - 25

SP - 107

EP - 114

JO - Dermatitis : contact, atopic, occupational, drug

JF - Dermatitis : contact, atopic, occupational, drug

SN - 1710-3568

IS - 3

ER -