Abstract
Objective: The study objective was to empirically identify subgroups of patients with obesity and investigate their association with postoperative weight change. Methods: A longitudinal analysis of 2,458 adults in the Longitudinal Assessment of Bariatric Surgery (LABS) study was used. Baseline data were used to identify subgroups. The outcome was 3-year weight change after bariatric surgery. Results: We identified four classes (subtypes) of obesity, which could be characterized as diabetes with low rates of high-density lipoprotein (Class 1), disordered eating (Class 2), mixed (Class 3), and extreme obesity with early onset (Class 4). Approximately 98% of participants in Class 1 had diabetes compared with < 40% in the other classes. There were high rates of binge eating in Class 2, and more than 92% of those in this class reported eating when not hungry. Class 4 was characterized by a higher BMI at baseline. Adults in Class 4 lost an average of 25.0% (males) and 30.3% (females) of their baseline weight over 3 years. In contrast with participants in Class 1, those in Classes 2 and 3 had significantly larger 3-year weight losses than their peers in Class 4. Conclusions: Obesity is a heterogeneous disease. Bariatric surgery may be most beneficial for adults with disordered eating.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1931-1937 |
| Number of pages | 7 |
| Journal | Obesity |
| Volume | 26 |
| Issue number | 12 |
| DOIs | |
| State | Published - Dec 1 2018 |
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ASJC Scopus subject areas
- Medicine (miscellaneous)
- Endocrinology, Diabetes and Metabolism
- Endocrinology
- Nutrition and Dietetics
Cite this
Association of Obesity Subtypes in the Longitudinal Assessment of Bariatric Surgery Study and 3-Year Postoperative Weight Change. / Field, Alison E.; Inge, Thomas H.; Belle, Steven H.; Johnson, Geoffrey S.; Wahed, Abdus S.; Pories, Walter J.; Spaniolas, Konstantinos; Mitchell, James E.; Pomp, Alfons; Dakin, Gregory F.; Wolfe, Bruce; Courcoulas, Anita P.
In: Obesity, Vol. 26, No. 12, 01.12.2018, p. 1931-1937.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Association of Obesity Subtypes in the Longitudinal Assessment of Bariatric Surgery Study and 3-Year Postoperative Weight Change
AU - Field, Alison E.
AU - Inge, Thomas H.
AU - Belle, Steven H.
AU - Johnson, Geoffrey S.
AU - Wahed, Abdus S.
AU - Pories, Walter J.
AU - Spaniolas, Konstantinos
AU - Mitchell, James E.
AU - Pomp, Alfons
AU - Dakin, Gregory F.
AU - Wolfe, Bruce
AU - Courcoulas, Anita P.
PY - 2018/12/1
Y1 - 2018/12/1
N2 - Objective: The study objective was to empirically identify subgroups of patients with obesity and investigate their association with postoperative weight change. Methods: A longitudinal analysis of 2,458 adults in the Longitudinal Assessment of Bariatric Surgery (LABS) study was used. Baseline data were used to identify subgroups. The outcome was 3-year weight change after bariatric surgery. Results: We identified four classes (subtypes) of obesity, which could be characterized as diabetes with low rates of high-density lipoprotein (Class 1), disordered eating (Class 2), mixed (Class 3), and extreme obesity with early onset (Class 4). Approximately 98% of participants in Class 1 had diabetes compared with < 40% in the other classes. There were high rates of binge eating in Class 2, and more than 92% of those in this class reported eating when not hungry. Class 4 was characterized by a higher BMI at baseline. Adults in Class 4 lost an average of 25.0% (males) and 30.3% (females) of their baseline weight over 3 years. In contrast with participants in Class 1, those in Classes 2 and 3 had significantly larger 3-year weight losses than their peers in Class 4. Conclusions: Obesity is a heterogeneous disease. Bariatric surgery may be most beneficial for adults with disordered eating.
AB - Objective: The study objective was to empirically identify subgroups of patients with obesity and investigate their association with postoperative weight change. Methods: A longitudinal analysis of 2,458 adults in the Longitudinal Assessment of Bariatric Surgery (LABS) study was used. Baseline data were used to identify subgroups. The outcome was 3-year weight change after bariatric surgery. Results: We identified four classes (subtypes) of obesity, which could be characterized as diabetes with low rates of high-density lipoprotein (Class 1), disordered eating (Class 2), mixed (Class 3), and extreme obesity with early onset (Class 4). Approximately 98% of participants in Class 1 had diabetes compared with < 40% in the other classes. There were high rates of binge eating in Class 2, and more than 92% of those in this class reported eating when not hungry. Class 4 was characterized by a higher BMI at baseline. Adults in Class 4 lost an average of 25.0% (males) and 30.3% (females) of their baseline weight over 3 years. In contrast with participants in Class 1, those in Classes 2 and 3 had significantly larger 3-year weight losses than their peers in Class 4. Conclusions: Obesity is a heterogeneous disease. Bariatric surgery may be most beneficial for adults with disordered eating.
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UR - http://www.scopus.com/inward/citedby.url?scp=85056405430&partnerID=8YFLogxK
U2 - 10.1002/oby.22287
DO - 10.1002/oby.22287
M3 - Article
C2 - 30421853
AN - SCOPUS:85056405430
VL - 26
SP - 1931
EP - 1937
JO - Obesity
JF - Obesity
SN - 1930-7381
IS - 12
ER -