Assessment of renal inflammation by ultrasound detection of phagocytosed lipid microbubbles

Ji Song, Kai Singbartl, Sanjiv Kaul, Fang Xu, Jonathan Lindner

Research output: Contribution to journalArticle

Abstract

Intravital microscopy of the cremaster muscle of mice was used to assess the microcirculatory behavior of fluorescein-labeled lipid microbubbles with and without TNFalpha-mediated inflammation. A good relation was found between the ultrasound signal from retained microbubbles and the degree of renal inflammation. It was concluded that noninvasive assessment of tissue inflammation is possible by ultrasound imaging of phagocytosed microbubbles.

Original languageEnglish (US)
JournalAnnals of Biomedical Engineering
Volume28
Issue numberSUPPL. 1
Publication statusPublished - 2000
Externally publishedYes

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ASJC Scopus subject areas

  • Biomedical Engineering

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