Assessment of renal inflammation by ultrasound detection of phagocytosed lipid microbubbles

Ji Song, Kai Singbartl, Sanjiv Kaul, Fang Xu, Jonathan Lindner

Research output: Contribution to journalArticle

Abstract

Intravital microscopy of the cremaster muscle of mice was used to assess the microcirculatory behavior of fluorescein-labeled lipid microbubbles with and without TNFalpha-mediated inflammation. A good relation was found between the ultrasound signal from retained microbubbles and the degree of renal inflammation. It was concluded that noninvasive assessment of tissue inflammation is possible by ultrasound imaging of phagocytosed microbubbles.

Original languageEnglish (US)
JournalAnnals of Biomedical Engineering
Volume28
Issue numberSUPPL. 1
StatePublished - 2000
Externally publishedYes

Fingerprint

Lipids
Ultrasonics
Muscle
Tissue
Imaging techniques
Intravital Microscopy
Tumor Necrosis Factor-alpha

ASJC Scopus subject areas

  • Biomedical Engineering

Cite this

Assessment of renal inflammation by ultrasound detection of phagocytosed lipid microbubbles. / Song, Ji; Singbartl, Kai; Kaul, Sanjiv; Xu, Fang; Lindner, Jonathan.

In: Annals of Biomedical Engineering, Vol. 28, No. SUPPL. 1, 2000.

Research output: Contribution to journalArticle

@article{a88b6b57da2e4598a63057b5697179f8,
title = "Assessment of renal inflammation by ultrasound detection of phagocytosed lipid microbubbles",
abstract = "Intravital microscopy of the cremaster muscle of mice was used to assess the microcirculatory behavior of fluorescein-labeled lipid microbubbles with and without TNFalpha-mediated inflammation. A good relation was found between the ultrasound signal from retained microbubbles and the degree of renal inflammation. It was concluded that noninvasive assessment of tissue inflammation is possible by ultrasound imaging of phagocytosed microbubbles.",
author = "Ji Song and Kai Singbartl and Sanjiv Kaul and Fang Xu and Jonathan Lindner",
year = "2000",
language = "English (US)",
volume = "28",
journal = "Annals of Biomedical Engineering",
issn = "0090-6964",
publisher = "Springer Netherlands",
number = "SUPPL. 1",

}

TY - JOUR

T1 - Assessment of renal inflammation by ultrasound detection of phagocytosed lipid microbubbles

AU - Song, Ji

AU - Singbartl, Kai

AU - Kaul, Sanjiv

AU - Xu, Fang

AU - Lindner, Jonathan

PY - 2000

Y1 - 2000

N2 - Intravital microscopy of the cremaster muscle of mice was used to assess the microcirculatory behavior of fluorescein-labeled lipid microbubbles with and without TNFalpha-mediated inflammation. A good relation was found between the ultrasound signal from retained microbubbles and the degree of renal inflammation. It was concluded that noninvasive assessment of tissue inflammation is possible by ultrasound imaging of phagocytosed microbubbles.

AB - Intravital microscopy of the cremaster muscle of mice was used to assess the microcirculatory behavior of fluorescein-labeled lipid microbubbles with and without TNFalpha-mediated inflammation. A good relation was found between the ultrasound signal from retained microbubbles and the degree of renal inflammation. It was concluded that noninvasive assessment of tissue inflammation is possible by ultrasound imaging of phagocytosed microbubbles.

UR - http://www.scopus.com/inward/record.url?scp=0034499312&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034499312&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:0034499312

VL - 28

JO - Annals of Biomedical Engineering

JF - Annals of Biomedical Engineering

SN - 0090-6964

IS - SUPPL. 1

ER -