### Abstract

An optoacoustic imaging algorithm uses backprojection of the time-resolved velocity potential to map the sources of pressure waves detected by an array of acoustic detectors. The relationship between pressure (P) and velocity potential (vp) is P = -rho*d(vp)/dt, or vp = -Integral(P dt)/rho where rho is density, t is time, and d(vp)/dt is the time derivative of the velocity potential. In a forward calculation, a computer simulation can predict the complex pressure waves arriving at each of an array of detectors due to any arbitrary spatial distribution of initial pressure generation. In an inverse calculation, such computer-simulated experimental measurements are used to spatially map the initial pressure source which in optoacoustic imaging corresponds to the initial distribution of pulsed laser energy deposition. Hence, the performance of the inverse calculation as an image reconstruction algorithm could be tested using ideal computer-simulated data. In this report, the image reconstruction algorithm was systematically tested to specify the expected performance under optimal conditions, to illustrate the source/detector geometries that frustrate image reconstruction, and to assess the impact of measurement noise. Typical reconstruction errors were +/- 20%.

Original language | English (US) |
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Title of host publication | Proceedings of SPIE - The International Society for Optical Engineering |

Editors | A.A. Oraevsky |

Pages | 146-152 |

Number of pages | 7 |

Volume | 4618 |

DOIs | |

State | Published - 2002 |

Event | Biomedical Optoacoustics III - San Jose, CA, United States Duration: Jan 20 2002 → Jan 21 2002 |

### Other

Other | Biomedical Optoacoustics III |
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Country | United States |

City | San Jose, CA |

Period | 1/20/02 → 1/21/02 |

### Fingerprint

### Keywords

- Biomedical optics
- Imaging
- Optoacoustic
- Photoacoustic

### ASJC Scopus subject areas

- Electrical and Electronic Engineering
- Condensed Matter Physics

### Cite this

*Proceedings of SPIE - The International Society for Optical Engineering*(Vol. 4618, pp. 146-152) https://doi.org/10.1117/12.469859

**Assessing the performance and limits of an optoacoustic image reconstruction algorithm using computer-simulated experimental measurements.** / Jacques, Steven.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

*Proceedings of SPIE - The International Society for Optical Engineering.*vol. 4618, pp. 146-152, Biomedical Optoacoustics III, San Jose, CA, United States, 1/20/02. https://doi.org/10.1117/12.469859

}

TY - GEN

T1 - Assessing the performance and limits of an optoacoustic image reconstruction algorithm using computer-simulated experimental measurements

AU - Jacques, Steven

PY - 2002

Y1 - 2002

N2 - An optoacoustic imaging algorithm uses backprojection of the time-resolved velocity potential to map the sources of pressure waves detected by an array of acoustic detectors. The relationship between pressure (P) and velocity potential (vp) is P = -rho*d(vp)/dt, or vp = -Integral(P dt)/rho where rho is density, t is time, and d(vp)/dt is the time derivative of the velocity potential. In a forward calculation, a computer simulation can predict the complex pressure waves arriving at each of an array of detectors due to any arbitrary spatial distribution of initial pressure generation. In an inverse calculation, such computer-simulated experimental measurements are used to spatially map the initial pressure source which in optoacoustic imaging corresponds to the initial distribution of pulsed laser energy deposition. Hence, the performance of the inverse calculation as an image reconstruction algorithm could be tested using ideal computer-simulated data. In this report, the image reconstruction algorithm was systematically tested to specify the expected performance under optimal conditions, to illustrate the source/detector geometries that frustrate image reconstruction, and to assess the impact of measurement noise. Typical reconstruction errors were +/- 20%.

AB - An optoacoustic imaging algorithm uses backprojection of the time-resolved velocity potential to map the sources of pressure waves detected by an array of acoustic detectors. The relationship between pressure (P) and velocity potential (vp) is P = -rho*d(vp)/dt, or vp = -Integral(P dt)/rho where rho is density, t is time, and d(vp)/dt is the time derivative of the velocity potential. In a forward calculation, a computer simulation can predict the complex pressure waves arriving at each of an array of detectors due to any arbitrary spatial distribution of initial pressure generation. In an inverse calculation, such computer-simulated experimental measurements are used to spatially map the initial pressure source which in optoacoustic imaging corresponds to the initial distribution of pulsed laser energy deposition. Hence, the performance of the inverse calculation as an image reconstruction algorithm could be tested using ideal computer-simulated data. In this report, the image reconstruction algorithm was systematically tested to specify the expected performance under optimal conditions, to illustrate the source/detector geometries that frustrate image reconstruction, and to assess the impact of measurement noise. Typical reconstruction errors were +/- 20%.

KW - Biomedical optics

KW - Imaging

KW - Optoacoustic

KW - Photoacoustic

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U2 - 10.1117/12.469859

DO - 10.1117/12.469859

M3 - Conference contribution

AN - SCOPUS:0036400007

VL - 4618

SP - 146

EP - 152

BT - Proceedings of SPIE - The International Society for Optical Engineering

A2 - Oraevsky, A.A.

ER -