Assessing delay discounting in mice

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Delay discounting (also intertemporal choice or impulsive choice) is the process bywhich delayed outcomes, such as delayed food delivery, are valued less than the same outcomes delivered immediately or with a shorter delay. This process is of interest because many psychopathologies, including substance dependence, pathological gambling, attention deficit hyperactivity disorder, and conduct disorder, are characterized by heightened levels of delay discounting. Some of these disorders are heritable, and data indicate that delay discounting also has a genetic component. To identify the genes underlying the delay discounting decision-making process and genetic correlates of heightened discounting, researchers have used mouse models. This unit describes a protocol for generating delay discounting behavior in mice and discusses analysis techniques for such behavior.

Original languageEnglish (US)
Article number8.30
JournalCurrent Protocols in Neuroscience
Issue numberSUPPL.66
DOIs
StatePublished - 2014

Fingerprint

Genetic Phenomena
Conduct Disorder
Gambling
Attention Deficit Disorder with Hyperactivity
Psychopathology
Substance-Related Disorders
Decision Making
Research Personnel
Delay Discounting
Food
Genes

Keywords

  • Decision-making
  • Hyperbolic
  • Impulsive choice
  • Indifference point
  • Intertemporal choice
  • Mouse behavior
  • Subjective value

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Assessing delay discounting in mice. / Mitchell, Suzanne.

In: Current Protocols in Neuroscience, No. SUPPL.66, 8.30, 2014.

Research output: Contribution to journalArticle

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