TY - JOUR
T1 - Assessing benefits and harms of hormone replacement therapy
T2 - Clinical applications
AU - Nelson, Heidi D.
N1 - Copyright:
Copyright 2018 Elsevier B.V., All rights reserved.
PY - 2002/8/21
Y1 - 2002/8/21
N2 - An estimated one third of postmenopausal women in the United States use hormone replacement therapy (HRT) to treat symptoms of menopause and prevent chronic conditions. In the context of this widespread use, evidence has been growing about the potential harms of HRT, particularly regarding long-term use. Physicians and patients are often confused about how to use results of studies in individual cases. This article applies the current state of evidence for the benefits and harms of HRT to management decisions in 4 clinical situations. Patient preferences, as well as evidence, are important for these decisions. Benefits and harms need to be readdressed periodically to apply newly published evidence and to reassess emerging risks, comorbidities, and needs of individuals.
AB - An estimated one third of postmenopausal women in the United States use hormone replacement therapy (HRT) to treat symptoms of menopause and prevent chronic conditions. In the context of this widespread use, evidence has been growing about the potential harms of HRT, particularly regarding long-term use. Physicians and patients are often confused about how to use results of studies in individual cases. This article applies the current state of evidence for the benefits and harms of HRT to management decisions in 4 clinical situations. Patient preferences, as well as evidence, are important for these decisions. Benefits and harms need to be readdressed periodically to apply newly published evidence and to reassess emerging risks, comorbidities, and needs of individuals.
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U2 - 10.1001/jama.288.7.882
DO - 10.1001/jama.288.7.882
M3 - Short survey
C2 - 12186606
AN - SCOPUS:0037151579
SN - 0098-7484
VL - 288
SP - 882
EP - 884
JO - JAMA
JF - JAMA
IS - 7
ER -